NICU Infants & SNHL: Experience of a western Sicily tertiary care centre

Introduction: The variability of symptoms and signs caused by central nervous system (CNS) lesions make multiple sclerosis difficult to recognize,Introduction: This study adds the evaluation of the independent etiologic factors that may play a role in the development of SNHL in a NICU population. We compared neonatal intensive care unit NICU infants with sensorineural hearing loss SNHL to age and gender matched normal hearing NICU controls. Materials and methods: 284 consecutive NICU infants positive to the presence of risk indicators associated with permanent congenital, delayed-onset, or progressive hearing loss underwent to global audiological assessment. The following risk factors were …

Isolation and characterization of circulating exosomes from blood in brain tumors

Exosomes (EXs) are crucial in mediating intercellular communication in physiological and pathological conditions. Accordingly, tumor-secreted EXs play an important role in regulating tumor malignancy. Tumor-derived exosomes contain proteins, mRNAs, and miRNAs, which can be delivered between different types of cells and even transferred to distant locations to influence the biological activities of tumors, such as proliferation, invasion and metastasis (1). Clinically, tumor-derived EXs may represent a target for therapeutic intervention and for the development of early diagnostic biomarkers (2). In our laboratory, we have focused on the isolation, morphological analyses, determination of par…

Acarine Biodiversity in the Natural and Human Sphere