0000000000341751
AUTHOR
Brian Vila Auli
Síndrome hepatopulmonar en paciente con adenocarcinoma de colon con metástasis hepáticas y sin hepatopatía crónica conocida
El sindrome hepatopulmonar comprende una triada clinica caracterizada por desoxigenacion arterial, dilataciones vasculares intrapulmonares y hepatopatia. Se han descrito tanto casos agudos como cronicos, y la causa mas frecuente es la cirrosis. El mecanismo fisiopatologico principal es la dilatacion de los vasos pulmonares, que produce una alteracion del intercambio gaseoso. Se ha implicado la mayor produccion pulmonar de oxido nitrico como mecanismo patogenico principal de la vasodilatacion, aunque tambien se ha relacionado el desequilibrio entre sustancias vasodilatadoras y vasoconstrictoras. Describimos un caso en el que se produjo un sindrome hepatopulmonar en un paciente afectado de un…
Hepatopulmonary Syndrome in a Patient With Adenocarcinoma of the Colon Metastatic to the Liver and No Apparent Chronic Liver Disease
Hepatopulmonary syndrome consists of a clinical triad: arterial blood deoxygenation, intrapulmonary vasodilation, and liver disease. Both acute and chronic cases of this syndrome have been reported, and the most common cause is cirrhosis. The principle disease mechanism is dilation of the pulmonary blood vessels causing alterations in gas exchange. Increased pulmonary production of nitric acid has been implicated as the primary pathogenic mechanism of vasodilation although it has also been associated with imbalance between vasodilators and vasoconstrictors. We describe the case of a patient with hepatopulmonary syndrome and adenocarcinoma of the colon with metastases to a previously healthy…