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RESEARCH PRODUCT
Hepatopulmonary Syndrome in a Patient With Adenocarcinoma of the Colon Metastatic to the Liver and No Apparent Chronic Liver Disease
Conrado Fernández RodríguezPilar Bañuls PoloDiego GarcíaBrian Vila AuliJulio Marín Pardosubject
Malemedicine.medical_specialtyCirrhosisColonVasodilationDiseaseAdenocarcinomaChronic liver diseaseGastroenterologyLiver diseaseLiver Function TestsInternal medicineHumansMedicineHepatopulmonary syndromebusiness.industryLiver NeoplasmsColonoscopyGeneral MedicineMiddle Agedmedicine.diseaseLiverColonic NeoplasmsArterial bloodAdenocarcinomaTomography X-Ray ComputedbusinessHepatopulmonary Syndromedescription
Hepatopulmonary syndrome consists of a clinical triad: arterial blood deoxygenation, intrapulmonary vasodilation, and liver disease. Both acute and chronic cases of this syndrome have been reported, and the most common cause is cirrhosis. The principle disease mechanism is dilation of the pulmonary blood vessels causing alterations in gas exchange. Increased pulmonary production of nitric acid has been implicated as the primary pathogenic mechanism of vasodilation although it has also been associated with imbalance between vasodilators and vasoconstrictors. We describe the case of a patient with hepatopulmonary syndrome and adenocarcinoma of the colon with metastases to a previously healthy liver.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-09-01 | Archivos de Bronconeumología ((English Edition)) |