0000000000341975

AUTHOR

Ziad A. Massy

showing 4 related works from this author

Incidence of Kidney Replacement Therapy and Subsequent Outcomes Among Patients With Systemic Lupus Erythematosus: Findings From the ERA Registry.

2022

RATIONALE AND OBJECTIVE: There is a dearth of data characterizing patients requiring kidney replacement therapy (KRT) for kidney failure due to systemic lupus erythematosus (SLE) and their clinical outcomes. The aim of this study was to describe trends in incidence and prevalence of KRT among these patients as well as to compare their outcomes to patients treated with KRT for diseases other than SLE.STUDY DESIGN: Retrospective cohort study based on kidney registry data.SETTING & PARTICIPANTS: Patients recorded in 14 registries of patients receiving kidney replacement therapy that provided data to the European Renal Association (ERA) Registry between 1992 and 2016.PREDICTOR: SLE as cause…

Malekidney diseasemedicine.medical_treatmentMAINTENANCE DIALYSIS030232 urology & nephrologyLupus nephritislupus nephritis (LN)0302 clinical medicineLupus Erythematosus Systemickidney replacement therapy (KRT)RegistriesRenal InsufficiencyKidney transplantationRISKeducation.field_of_studyKidneyregistry studyIncidence (epidemiology)IncidenceSTAGE RENAL-DISEASELupus Nephritis3. Good healthEuropeRenal Replacement Therapymedicine.anatomical_structureNephrologySURVIVALFemalemedicine.medical_specialtyprevalencePopulationkidney transplantationUNITED-STATESsurvival03 medical and health sciencesAFRICAN-AMERICAN PATIENTSInternal medicinemedicineHumansESRDeducationNEPHRITISDialysisRetrospective Studies030203 arthritis & rheumatologyProportional hazards modelbusiness.industryTRANSPLANTATIONMORTALITYRetrospective cohort studymedicine.diseasekidney failureend-stage renal disease (ESRD)3121 General medicine internal medicine and other clinical medicineSystemic lupus erythematosus (SLE)Kidney Failure ChronicprognosisbusinessAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
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Supplemented ERA-EDTA Registry data evaluated the frequency of dialysis, kidney transplantation, and comprehensive conservative management for patien…

2021

The aims of this study were to determine the frequency of dialysis and kidney transplantation and to estimate the regularity of comprehensive conservative management (CCM) for patients with kidney failure in Europe. This study uses data from the ERA-EDTA Registry. Additionally, our study included supplemental data from Armenia, Germany, Hungary, Ireland, Kosovo, Luxembourg, Malta, Moldova, Montenegro, Slovenia and additional data from Israel, Italy, Slovakia using other information sources. Through an online survey, responding nephrologists estimated the frequency of CCM (i.e. planned holistic care instead of kidney replacement therapy) in 33 countries. In 2016, the overall incidence of rep…

0301 basic medicinemedicine.medical_treatment[SDV]Life Sciences [q-bio]030232 urology & nephrologyConservative TreatmentDISEASE0302 clinical medicineGermanyMedicine and Health SciencesRegistriesRenal InsufficiencyKidney transplantationeducation.field_of_studyhemodialysisGreeceRENAL REPLACEMENT THERAPY3. Good healthEuropeperitoneal dialysisItalyNephrologyHemodialysismedicine.medical_specialtyPopulationhemodialysis [Keywords]Peritoneal dialysis03 medical and health sciencesRenal DialysisInternal medicinemedicineHumansRenal replacement therapyeducationDialysisEdetic AcidPortugalbusiness.industryHome hemodialysisCAREmedicine.disease3126 Surgery anesthesiology intensive care radiologyKidney TransplantationTransplantation030104 developmental biologySpainKidney Failure ChronicDONATIONbusinessIrelandtransplantationKidney international
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Inflammation is an amplifier of lung congestion by high lv filling pressure in hemodialysis patients: a longitudinal study

2019

Introduction Since infammation alters vascular permeability, including vascular permeability in the lung, we hypothesized that it can be an amplifer of lung congestion in a category of patients at high risk for pulmonary oedema like end stage kidney disease (ESKD) patients. Objective and methods We investigated the efect modifcation by systemic infammation (serum CRP) on the relationship between a surrogate of the flling pressure of the LV [left atrial volume indexed to the body surface area (LAVI)] and lung water in a series of 220 ESKD patients. Lung water was quantifed by the number of ultrasound B lines (US-B) on lung US. Six-hundred and three recordings were performed during a 2-year f…

Nephrologymedicine.medical_specialtymedicine.medical_treatment030232 urology & nephrologyInflammationVascular permeabilityInfammation030204 cardiovascular system & hematologySystemic inflammation03 medical and health sciences0302 clinical medicineRenal DialysisPulmonary edemaInternal medicinemedicineHumansLongitudinal StudiesLung congestionESRDLungInflammationBody surface areaLungbusiness.industryCardiovascular riskPulmonary edemamedicine.diseasemedicine.anatomical_structureNephrologyHemodialysisCardiologyHemodialysismedicine.symptombusinessJournal of Nephrology
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A randomized multicenter trial on a lung ultrasound-guided treatment strategy in patients on chronic hemodialysis with high cardiovascular risk

2021

Lung congestion is a risk factor for all-cause and cardiovascular mortality in patients on chronic hemodialysis, and its estimation by ultrasound may be useful to guide ultrafiltration and drug therapy in this population. In an international, multi-center randomized controlled trial (NCT02310061) we investigated whether a lung ultrasound-guided treatment strategy improved a composite end point (all-cause death, non-fatal myocardial infarction, decompensated heart failure) vs usual care in patients receiving chronic hemodialysis with high cardiovascular risk. Patient-Reported Outcomes (Depression and the Standard Form 36 Quality of Life Questionnaire, SF36) were assessed as secondary outcome…

cardiovascular riskmedicine.medical_specialtymedicine.medical_treatmentPopulationlung congestionlaw.inventionKidney FailureRandomized controlled trialRenal DialysisRisk FactorslawMulticenter trialInternal medicineHumansMedicineChronicRisk factorESRDeducationLungUltrasonography InterventionalDialysisUltrasonographylung ultrasoundeducation.field_of_studyInterventionalbusiness.industryHazard ratiochronic kidney failuremedicine.diseaseESRD; cardiovascular risk; chronic kidney failure; heart failure hemodialysis; lung congestion; lung ultrasoundHeart Disease Risk FactorsCardiovascular DiseasesNephrologyHeart failureQuality of LifeKidney Failure ChronicHemodialysisheart failure hemodialysisbusinessKidney international
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