0000000000343669

AUTHOR

Rustem Khazipov

0000-0002-6763-2841

showing 2 related works from this author

Early patterns of electrical activity in the developing cerebral cortex of humans and rodents.

2006

International audience; During prenatal and early postnatal development, the cerebral cortex exhibits synchronized oscillatory network activity that is believed to be essential for the generation of neuronal cortical circuits. The nature and functional role of these early activity patterns are of central interest in neuroscience. Much of the research is performed in rodents and in vitro, but how closely do these model systems relate to the human fetal brain? In this review, we compare observations in humans with in vivo and in vitro rodent data, focusing on particular oscillatory activity patterns that share many common features: delta brushes, spindle bursts and spindle-like oscillations. …

PeriodicityMESH: PeriodicityRodentPeriod (gene)Central nervous systemModels NeurologicalMESH: NeuronsNeurological disorder[SDV.BC]Life Sciences [q-bio]/Cellular Biology03 medical and health sciences0302 clinical medicineMESH: Models Neurologicalbiology.animalmedicineAnimalsHumansMESH: Animals[SDV.BC] Life Sciences [q-bio]/Cellular Biology030304 developmental biologyCerebral CortexNeurons0303 health sciencesMESH: HumansbiologyGeneral Neurosciencemedicine.diseaseMESH: Cerebral CortexDevelopmental disorderElectrophysiologymedicine.anatomical_structureMESH: Nerve NetCerebral cortexHuman fetalNerve NetPsychologyNeuroscience030217 neurology & neurosurgery
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Neuronal Activity Patterns in the Developing Barrel Cortex

2017

International audience; The developing barrel cortex reveals a rich repertoire of neuronal activity patterns, which have been also found in other sensory neocortical areas and in other species including the somatosensory cortex of preterm human infants. The earliest stage is characterized by asyn-chronous, sparse single-cell firing at low frequencies. During the second stage neurons show correlated firing, which is initially mediated by electrical synapses and subsequently transforms into network bursts depending on chemical synapses. Activity patterns during this second stage are synchronous plateau assemblies, delta waves, spindle bursts and early gamma oscillations (EGOs). In newborn rod…

0301 basic medicineRodentiaSensory systemReviewDevelopmentBiologySomatosensory systemRodentsGABA03 medical and health sciences0302 clinical medicineAnimalsPremovement neuronal activity[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Cortical SynchronizationNeuronsSensory-evoked activitySensory stimulation therapyGeneral NeuroscienceSomatosensory CortexBarrel cortexBrain WavesSpontaneous activityDelta wave030104 developmental biologyElectrical Synapses[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]Neuroscience030217 neurology & neurosurgeryCortical SynchronizationNeuroscience
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