0000000000344012

AUTHOR

Kahl Gf

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Metabolism of metyrapone by a soluble enzyme system in rat liver.

1970

The formation of a metabolite of metyrapone by an oxygen sensitive soluble enzyme system in rat liver 105,000×g supernatant has been demonstrated. Enzyme activity requires the intact keto function of metyrapone.

MaleUltraviolet RaysMetabolitechemistry.chemical_elementOxygenchemistry.chemical_compoundEnzyme systemmedicineAnimalsBiotransformationPharmacologyMetyraponebiologyChemistryGeneral MedicineMetabolismMetyraponeEnzyme assayRatsBiochemistryLiverSpectrophotometryRat liverbiology.proteinMicrosomes LiverChromatography Thin LayerOxidoreductasesFunction (biology)NADPmedicine.drugNaunyn-Schmiedebergs Archiv fur Pharmakologie
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