Metabolism of metyrapone by a soluble enzyme system in rat liver.

6533b7d9fe1ef96bd126ce41

RESEARCH PRODUCT

Metabolism of metyrapone by a soluble enzyme system in rat liver.

subject

Male Ultraviolet Rays Metabolite chemistry.chemical_element Oxygen chemistry.chemical_compound Enzyme system medicine Animals Biotransformation Pharmacology Metyrapone biology Chemistry General Medicine Metabolism Metyrapone Enzyme assay Rats Biochemistry Liver Spectrophotometry Rat liver biology.protein Microsomes Liver Chromatography Thin Layer Oxidoreductases Function (biology)NADP medicine.drug

description

The formation of a metabolite of metyrapone by an oxygen sensitive soluble enzyme system in rat liver 105,000×g supernatant has been demonstrated. Enzyme activity requires the intact keto function of metyrapone.

year	journal	country	edition	language
1970-01-01	Naunyn-Schmiedebergs Archiv fur Pharmakologie

10.1007/bf00997099 https://pubmed.ncbi.nlm.nih.gov/4394454

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