0000000000344890

AUTHOR

Piotr Dziegiel

0000-0002-8292-1385

showing 2 related works from this author

Immune activation- and regulation-related patterns in stable hand transplant recipients

2016

Summary We assessed cell subsets and expression of a set of genes related to the T-cell populations in peripheral blood mononuclear cells to elucidate whether immune status of stable hand transplant recipients (HTx) differs from stable kidney transplant recipients (KTx). The study was conducted on five HTx 4.8 ± 1.7 years after transplantation and 30 stable KTx 7.9 ± 2.4 years after transplantation as well as 18 healthy volunteers. The research involved PBMC gene expression analysis of CD4, CD8, CTLA4, GZMB, FOXP3, IL10, IL4, ILR2A, NOTCH, PDCD1, PRF1, TGF-B, and TNF-A genes on a custom-designed low-density array (TaqMan) as well as flow cytometry assessment of lymphocyte subpopulations. HT…

AdultMaleT cellskidney transplantation030230 surgeryimmunomodulationPeripheral blood mononuclear cellGZMB03 medical and health sciences0302 clinical medicineTransplantation ImmunologymedicineHumansKidney transplantationTransplantationbusiness.industryFOXP3Middle Agedmedicine.diseaseTransplantationInterleukin 10Case-Control StudiesImmunologygene expressionFemale030211 gastroenterology & hepatologyrejectionbusinessCD8Hand transplantationhand transplantationTransplant International
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Effects of massage on the expression of proangiogenic markers in rat skin

2018

Introduction. Massage is a physiotherapeutic treatment, commonly used in both therapy and restoration of normal body functions. The aim of this work was to determine the effects of skin massage on stimulating the expression of angiogenesis-initiating factors, i.e. VEGF-A, FGF-2 (bFGF) and CD34 and on skin regeneration processes. Material and methods. The study was conducted on 48 Buffalo strain rats, randomly divided into two groups. In the first group (M, the massaged group), massage was applied five times a week for 7 weeks. In the second study group (C, the control group), the massage was omitted. Massage consisted of spiral movements at the plantar surface of skin for 5 min on each rear…

MaleVascular Endothelial Growth Factor AskinHistologyCD34FGF-2massageReal-Time Polymerase Chain Reaction01 natural sciencesVEGF-APathology and Forensic MedicineAndrology03 medical and health sciences0302 clinical medicineDownregulation and upregulationGene expressionMedicineAnimalsHumansRegenerationratCell ProliferationMessenger RNAMassageintegumentary systembiology010405 organic chemistrybusiness.industryRegeneration (biology)General MedicineImmunohistochemistry0104 chemical sciencesRatsqPCRGene Expression Regulation030220 oncology & carcinogenesisKi-67biology.proteinImmunohistochemistryKi-67Fibroblast Growth Factor 2CD34businessBiomarkersIHCFolia Histochemica et Cytobiologica
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