0000000000347307

AUTHOR

Claudiu Marian

Research and Science Today Supplement

In this issue are included scientific articles who debate problems from social science fields: development, power of the state, European policy, democracy, freedom of choice, social science. Authors talk about subjects as Sport policy and heroes in the Romanian communism, Food in war time in Transylvania, Global Security, Cyberspace, Postcommunism, Evaluation of some toxic compounds in water, Public policies. Research and Science Today Journal is a publication founded in 2011 and it is dedicated to the students of all levels (license, master and doctoral) of faculties in the country and abroad. We want to offer the participants the opportunity to present their scientific works in the follow…

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Research and Science Today Supplement 2/2014

In this supplement of Research and Science Today journal are included scientific articles which debate problems from social science fields, engineering sciences fields, legal sciences and medical sciences fields: European borders, social challanges, immigration flows, migration in Europa, syrian refugees in Romania, modernity, cultural identity, Ukraina and Crimeea, financial crisis, constructivist Europe, economic security, democratic regimes, unilateral separation, lobbying for migration policy, naturalism, migrant wave.Research and Science Today Journal is a publication founded in 2011 and it is dedicated to the students of all levels (license, master and doctoral) of faculties in the co…

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Research and Science Today

Research and Science Today Journal is a publication founded in 2011 and it is dedicated to the students of all levels (license, master and doctoral) of faculties in the country and abroad. We want to offer the participants the opportunity to present their scientific works in the following areas: Social Sciences, Economic Sciences, Legal Sciences, Humanities, Education Sciences, Engineering, Medicine and Sport.This journal provides students the opportunity to create and/or to improve their abilities to write scientific papers. So each appearance (two appearances per year at which we can add supplements) contains a number of papers written by students, masters and doctoral from the faculties …

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Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

Although endocannabinoids constitute one of the first lines of defense against pain, the anatomical locus and the precise receptor mechanisms underlying cannabinergic modulation of pain are uncertain. Clinical exploitation of the system is severely hindered by the cognitive deficits, memory impairment, motor disturbances and psychotropic effects resulting from the central actions of cannabinoids. We deleted the type 1 cannabinoid receptor (CB1) specifically in nociceptive neurons localized in the peripheral nervous system of mice, preserving its expression in the CNS, and analyzed these genetically modified mice in preclinical models of inflammatory and neuropathic pain. The nociceptor-spec…

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