0000000000349600

AUTHOR

Alessandro De Sire

0000-0002-5541-8346

showing 5 related works from this author

Can Vitamin D deficiency influence muscle perfomance in post-menopausal women? A multicenter retrospective study

2018

Background: The presence of the vitamin D receptor (VDR) has been recently demonstrated in human muscle supporting the theory of a role of vitamin D in the proliferation and differentiation of muscle cells. So far only few studies investigated the association between vitamin D and muscle performance in postmenopausal women. Aim: To define the functional impact of vitamin D deficiency. Design: Multicenter retrospective study. Setting: Five Italian outpatient services of Physical and Rehabilitation Medicine (PRM). Population: Postmenopausal women. Methods: We divided the population in two groups based on the threshold of 30 ng/mL as cut-off to define sufficient and insufficient serum levels o…

medicine.medical_specialtySarcopeniaPopulation030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseWalkingGastroenterologyCalcitriol receptorvitamin D deficiency03 medical and health sciencesGrip strength0302 clinical medicineHand strengthInternal medicinemedicineVitamin D and neurologyHumans030212 general & internal medicineMuscle StrengthVitamin DeducationAgedRetrospective Studieseducation.field_of_studyVitamin D post menopausal women Knee isometric extension strenght hand grip strenghtHand Strengthbusiness.industrySettore MED/34 - Medicina Fisica E RiabilitativaRehabilitationMiddle Agedmedicine.diseaseVitamin D DeficiencyPostmenopausePhysical FitnessPhysical therapyLean body massFemalevitamin D vitamin D deficiency sarcopenia muscle strengthbusiness
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Multifactorial Assessment of Risk of Falling in 753 Post-Menopausal Women: A Multicenter Cross-Sectional Study by the Italian Group for the Study of …

2020

Giovanni Iolascon,1 Alessandro de Sire,1– 3 Dario Calafiore,1,4 Maria Grazia Benedetti,5 Carlo Cisari,2,6 Giulia Letizia Mauro,7 Silvia Migliaccio,8 Ranuccio Nuti,9 Giuseppina Resmini,10 Stefano Gonnelli,9 Antimo Moretti1 1Department of Medical and Surgical Specialties and Dentistry, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2Physical and Rehabilitative Medicine, Department of Health Sciences, University of Eastern Piedmont “A. Avogadro”, Novara, Italy; 3Rehabilitation Unit, “Mons L. Novarese” Hospital, Vercelli, Moncrivello, Italy; 4Section of Neuromotor Rehabilitation, Department of Neuroscience, ASST Ca…

walking speed.medicine.medical_specialtyCross-sectional studymedicine.medical_treatmentOsteoporosiswalking speedboneaccidental falls osteoporosis walking speed fractures bone rehabilitationBone remodelingrehabilitationFractures Bone03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineVitamin D and neurologyHumansMedicineosteoporosi030212 general & internal medicineVitamin DAgedOriginal ResearchAged 80 and overRehabilitationaccidental fallbusiness.industryRC952-954.6General Medicinefracturesmedicine.diseaseosteoporosisPostmenopausePreferred walking speedCross-Sectional StudiesItalyGeriatricsfractureClinical Interventions in AgingCohortrehabilitation.Population studyFemaleaccidental fallsGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryClinical Interventions in Aging
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Adolescent idiopathic scoliosis screening: Could a school-based assessment protocol be useful for an early diagnosis?

2020

BACKGROUND: Adolescent idiopathic scoliosis screening still needs a considerable implementation, particularly throughout a school-based assessment protocol. OBJECTIVE: This study aims to evaluate the effectiveness of clinical examinations currently in use for the diagnosis of adolescent idiopathic scoliosis, through a survey carried out in secondary schools to standardize a screening protocol that could be generalized. METHODS: In their classrooms, the adolescents underwent an idiopathic scoliosis screening through three examinations: Adam’s test, axial trunk rotation (ATR) and plumb line. In case of single positivity to one of the three examinations, a column X-ray examination was recommen…

MalePediatricsmedicine.medical_specialtyAdolescentPhysical Therapy Sports Therapy and RehabilitationDiagnostic SpecificityIdiopathic scoliosisScoliosis03 medical and health sciences0302 clinical medicineTrunk rotationmedicineHumansMass ScreeningOrthopedics and Sports Medicine030212 general & internal medicineSchool-based assessmentChildPhysical ExaminationPlumb bobSchool Health ServicesProtocol (science)030222 orthopedicsSchoolsbusiness.industryRehabilitationScoliosis spine deformities adam’s test axial trunk rotation plumb linemedicine.diseaseTest (assessment)Cross-Sectional StudiesEarly DiagnosisScoliosisFemalebusinessJournal of Back and Musculoskeletal Rehabilitation
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Early Denosumab for the prevention of osteoporotic fractures in breast cancer women undergoing aromatase inhibitors: A case-control retrospective stu…

2021

BACKGROUND: Aromatase inhibitors (AIs) might have a detrimental impact on bone health in breast cancer (BC) women. Denosumab has been shown to reduce the risk of fractures, but the appropriate time for starting is yet to be clearly defined. OBJECTIVE: To evaluate the effects of early treatment with Denosumab (⩽ 12 months after starting AIs) compared to a delayed treatment in BC women. METHODS: In this retrospective case-control study, we included medical records of BC post-menopausal women, treated with AIs therapy; they were divided as: study group (starting Denosumab ⩽ 12 months after AIs) and control group (> 12 months). At the baseline (T0) and at 18 months (T1), we evaluated the lum…

Osteoporosisrisk of fracture0302 clinical medicineRetrospective StudieBone DensityOrthopedics and Sports Medicine030212 general & internal medicineAromataseOsteoporosis PostmenopausalbiologyBone Density Conservation AgentsAromatase InhibitorsSettore MED/34 - Medicina Fisica E RiabilitativaMedical recordRehabilitationMiddle Agedmedicine.anatomical_structureDenosumab030220 oncology & carcinogenesisOsteoporosis risk of fractures breast cancer denosumab bone healthFemaleDenosumabCase-Control StudieBreast NeoplasmHumanmedicine.drugmedicine.medical_specialtyBone Density Conservation AgentPhysical Therapy Sports Therapy and RehabilitationBreast NeoplasmsBone health03 medical and health sciencesbreast cancerBreast cancerInternal medicinemedicineAromatase InhibitorHumansbone healthFemoral neckAgedRetrospective Studiesrisk of fracturesbusiness.industryOsteoporosiRetrospective cohort studymedicine.diseaseCase-Control Studiesbiology.proteinbusinessOsteoporotic Fractures
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Pharmacological Treatment for Acute Traumatic Musculoskeletal Pain in Athletes

2021

Pain management is a crucial issue for athletes who train and compete at the highest performance levels. There are still evidence gaps for the use of analgesics for sports injuries despite the growing interest in training and competition settings. However, high-quality research is needed to determine the most appropriate and optimal timing and formulations in non-steroidal anti-inflammatory drug and opioid management, particularly given the strictness of anti-doping regulations. Indeed, the role of pharmacological therapy in reducing acute traumatic pain in athletes should still be addressed to minimize the timing of return to sport. Therefore, the aim of this comprehensive review was to su…

Musculoskeletal painMedicine (General)medicine.medical_specialtyPharmacological therapymedicine.medical_treatmentReviewathletic injurierehabilitationPharmacological treatmentReturn to sportathletic injuriesR5-920Musculoskeletal PainHumansMedicineRehabilitationbiologyAthletesbusiness.industrysport medicineGeneral MedicinePain managementbiology.organism_classificationtraumapain managementOpioidAthletesPhysical therapybusinessSportsreturn to sportmedicine.drugMedicina
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