0000000000351478
AUTHOR
Licastro F
showing 11 related works from this author
Polymorphisms of pro-inflammatory genes and Alzheimer's disease risk.
2006
Association between the Polymorphism of CCR5 and Alzheimer's Disease: results of a study performed on male and female patients from Northern Italy
2006
Is immunotherapy an effective treatment for Alzheimer's disease?
2004
Abstract Immunotherapy in patients with Alzheimer's disease (AD) is rapidly becoming a hot topic of modern geriatric and clinical gerontology. Current views see immunization with Aβ peptide, the amyloidogenic protein found in senile plaque of AD patient's brains, or the infusion of preformed antibody specific for human Aβ, as possible therapeutic approaches to improve the cognitive status in the disease. Animal models of the disease have provided positive results from both approaches. Thus, an initial clinical trial using immunization with human Aβ in AD patients was started, but then shortly halted because of an unusually high incidence (6%) of meningoencephalitis. A long and currently ong…