Polymorphisms of pro-inflammatory genes and Alzheimer's disease risk.

Association between the Polymorphism of CCR5 and Alzheimer's Disease: results of a study performed on male and female patients from Northern Italy

Is immunotherapy an effective treatment for Alzheimer's disease?

Abstract Immunotherapy in patients with Alzheimer's disease (AD) is rapidly becoming a hot topic of modern geriatric and clinical gerontology. Current views see immunization with Aβ peptide, the amyloidogenic protein found in senile plaque of AD patient's brains, or the infusion of preformed antibody specific for human Aβ, as possible therapeutic approaches to improve the cognitive status in the disease. Animal models of the disease have provided positive results from both approaches. Thus, an initial clinical trial using immunization with human Aβ in AD patients was started, but then shortly halted because of an unusually high incidence (6%) of meningoencephalitis. A long and currently ong…

PROTECTIVE DETERMINANTS AGAINST CARDIOVASCULAR DISEASES ARE PRESENT IN GENETIC BACKGROUND OF CENTENARIANS.

Age-related inflammatory disease: role of genetics and gender in the pathophisiology of Alzheimer’s disease

Age at onset of Alzheimer disease and Tumor Necrosis Factor-Alpha -308A/G Polymorphism. Alzheimer’s and Parkinson diseases:

PROTECTIVE DETERMINANTS AGAINST CARDIOVASCULAR DISEASES ARE PRESENT IN GENETIC BACKGROUND OF CENTENARIANS

Ruolo del polimorfismo –308 A/G del gene del Tumor Necrosis Factor-a nell’età di insorgenza della malattia di Alzheimer

RUOLO DELLA CITOCHINA PRO-INFIAMMATORIA TNF NELL’INVECCHIAMENTO SENZA SUCCESSO E NELLA LONGEVITÀ

Associazione fra l’antigene HLA-A2 e la malattia di Alzheimer

Ruolo del recettore nACHR4 nella malattia d’Alzheimer: associazione con il polimorfismo C594T