Robust reliable control of uncertain discrete impulsive switched systems with state delays

Published version of an article in the journal: Mathematical Problems in Engineering. Also available from the publisher at: http://dx.doi.org/10.1155/2013/197819 Open access This paper is concerned with the problem of robust reliable control for a class of uncertain discrete impulsive switched systems with state delays, where the actuators are subjected to failures. The parameter uncertainties are assumed to be norm-bounded, and the average dwell time approach is utilized for the stability analysis and controller design. Firstly, an exponential stability criterion is established in terms of linear matrix inequalities (LMIs). Then, a state feedback controller is constructed for the underlyin…

Exploring the apparent properties and Q-markers for quality control of Cornus officinalis

Cornus officinalis Siebold & Zucc. has a high nutritious value and is widely used in food fields. To distinguish the quality of cornus in different areas, this research provided a new strategy for comprehensively evaluating cornus. As a result, 12 iridoid glycosides and 7 polyphenols were identified and quantified by UHPLC-Q-TOF/MS in 13 batches of samples from five different origins. Chromaticity analysis pointed out that pelargonidin-3-O-galactoside, total iridoids, and total polyphenols performed high relation with 1365*. Antioxidant activity and inhibition of α-glucosidase effect correlated with the chemical analysis suggested that iridoid glycosides and polyphenols should represent…

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are established measures of subclinical atherosclerosis that each predicts future cardiovascular disease events. We conducted a meta-analysis of genome-wide association data in 31,211 participants of European ancestry from nine large studies in the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. We then sought additional evidence to support our findings among 11,273 individuals using data from seven additional studies. In the combined meta-analysis, we identified three genomic regions associated with common carotid intima media thickness and two different regions a…

Output Feedback Control of Discrete Impulsive Switched Systems with State Delays and Missing Measurements

Published version of an article in the journal: Mathematical Problems in Engineering. Also available from the publisher at: http://dx.doi.org/10.1155/2013/283426 Open Access This paper is concerned with the problem of dynamic output feedback (DOF) control for a class of uncertain discrete impulsive switched systems with state delays and missing measurements. The missing measurements are modeled as a binary switch sequence specified by a conditional probability distribution. The problem addressed is to design an output feedback controller such that for all admissible uncertainties, the closed-loop system is exponentially stable in mean square sense. By using the average dwell time approach a…

Asynchronously switched control of discrete impulsive switched systems with time delays

This paper is concerned with the stabilization problem for a class of uncertain discrete impulsive switched delay systems under asynchronous switching. The so-called asynchronous switching means that the switches between the candidate controllers and system modes are asynchronous. By using the average dwell time (ADT) approach, sufficient conditions for the existence of an asynchronously switched controller is derived such that the resulting closed-loop system is exponentially stable. The desired controller gains and the admissible switching signals are obtained in terms of a set of matrix inequalities. A numerical example is given to illustrate the effectiveness of the proposed method.

40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

De novo loss-of-function KCNMA1 variants are associated with a new multiple malformation syndrome and a broad spectrum of developmental and neurological phenotypes

Abstract KCNMA1 encodes the large-conductance Ca2+- and voltage-activated K+ (BK) potassium channel α-subunit, and pathogenic gain-of-function variants in this gene have been associated with a dominant form of generalized epilepsy and paroxysmal dyskinesia. Here, we genetically and functionally characterize eight novel loss-of-function (LoF) variants of KCNMA1. Genome or exome sequencing and the participation in the international Matchmaker Exchange effort allowed for the identification of novel KCNMA1 variants. Patch clamping was used to assess functionality of mutant BK channels. The KCNMA1 variants p.(Ser351Tyr), p.(Gly356Arg), p.(Gly375Arg), p.(Asn449fs) and p.(Ile663Val) abolished the …