0000000000354732
AUTHOR
F. Nassir
Comparison of iceball diameter and temperature distribution achieved with 3-mm accuprobe cryoprobes in porcine and human liver tissue and human colorectal liver metastases in vitro.
Abstract We aimed to assess the thermal profile and size of iceballs produced by Accuprobe cryoprobes in fresh porcine and human liver and human colorectal cancer liver metastases in vitro to allow better planning of cryosurgical treatment of liver metastases. Iceballs were produced by a 20-min single freeze cycle using 8-mm cryoprobes in pig liver in a waterbath at 37°C ( n = 8) and 3-mm cryoprobes in pig liver ( n = 8), human liver ( n = 3), and human colorectal cancer liver metastases ( n = 8). The iceball diameters and the temperatures at different distances from the cryoprobe were measured. Mean iceball diameters produced by 8-mm cryoprobes in pig liver were 56.3 mm and varied from 38.…
Cholecystectomy in high-risk patients: A comparison between open cholecystectomy and laparoscopic cholecystectomy
SummaryLaparoscopic cholecystectomy offers many advantages, yet patients with a history of cardiopulmonary problems are at an increased risk because of the hemodynamic and respiratory effects of pneumoperitoneum. Between June 1990 and November 1997, a laparoscopic cholecystectomy was performed on 31 high risk patients [American Society of Anesthesiology (ASA) IV] and 40 conventional cholecystectomies were performed on patients with the same operative risk (ASA IV). In total, 15.5% (n = 11) of these patients experienced intraoperative cardiopulmonary complications, occurring with approximately the same frequency in both groups. General post-operative complications were seen in 28.2% (n=20) o…
Temperaturgradient und histologische Veränderungen bei der tierexperimentellen Kryotherapie der Leber
Bei 22 Schweinen wurden Kryolasionen mit 8 mm-AccuProbe Kryosonden erzeugt. Die Temperatur in unterschiedlichen Abstanden von der Kryosonde und die Eisballdurchmesser wurden gemessen und die Kryolasionen nach 24 h und 1 Woche histologisch untersucht. Unterschiedliche Gefrier-Auftauzyklen wurden angewendet: a: Einfaches Einfrieren (20 min); b: Doppeltes Einfrieren (20 min); c: Einfaches Einfrieren (40 min); d: Einfaches Einfrieren (20 min) & Pringle Manover. Die mittleren Eisballdurchmesser am Ende der Einfriervorgange waren 59 mm (a), 78 mm (b), 75 mm (d). Die mittleren Durchmesser der Zone wo eine Temperatur von ≤ -40 °C erzielt wurde war 37 mm (a) und 46 mm (b-d). Histologisch zeigte …