0000000000356735

AUTHOR

Tiziana Falco

showing 7 related works from this author

Ferulago nodosa Subsp. geniculata (Guss.) Troia & Raimondo from Sicily (Italy): Isolation of Essential Oil and Evaluation of Its Bioactivity

2020

Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area. The object of the present study is Sicilian F. nodosa subsp. geniculata (Guss.) Troia & Raimondo, classified as an endemic F. nodosa subspecies. Aerial parts of this plant species were subjected to hydrodistillation to obtain an essential oil. A total of 93 compounds were identified with 2,3,6-trimethyl benzaldehyde (19.0%), spathulenol (9.0%), (E)-caryophyllene (5.4%), and caryophyllene oxide (5.4%) as the main components. The biological activities of F. nodosa essential oil were also investigated. This oil showed an interesting antioxidant potential in a 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sul…

obesityantioxidantPharmaceutical ScienceFerulago nodosaSubspeciesAntioxidant potential030226 pharmacology & pharmacy01 natural sciencesArticleessential oilAnalytical Chemistrylaw.inventionlcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0302 clinical medicinelcsh:Organic chemistrylawDrug DiscoverySettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryEssential oilApiaceaeABTSdiabetesbiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationgas chromatography-mass spectrometry0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryCaryophyllene oxidediabeteChemistry (miscellaneous)Settore BIO/03 - Botanica Ambientale E ApplicataPlant speciesMolecular MedicineMolecules
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Almond (Prunus dulcis cv. Casteltermini) Skin Confectionery By-Products: New Opportunity for the Development of a Functional Blackberry (Rubus ulmifo…

2021

This work proposes for the first time a model for reusing almond (Prunus dulcis cv. Casteltermini from Sicily, Southern Italy) skin to formulate a new functional blackberry (Rubus ulmifolius Schott) jam. For this purpose, blackberries were analysed fresh and as jam, traditionally prepared with a minimum fruit amount of 80%. Different percentages of almond skin (20, 15, and 10% w/w) were added to jam. The phytochemical profile of enriched jam was investigated by LC-ESI/LTQOrbitrap/MS analyses. Anthocyanins, hydrolysable tannins, and triterpenoids were identified in a blackberry extract, while proanthocyanidins, flavonoids, and oxylipins were identified in an almond extract. The n-hexane extr…

AntioxidantPhysiologyDPPHmedicine.medical_treatmentClinical BiochemistryRM1-950carbohydrate hydrolysing enzymesPrunus dulcis cv. Casteltermini skin01 natural sciencesBiochemistrySensory analysisArticlechemistry.chemical_compound0404 agricultural biotechnologylipasemedicineGC–MS<i>Prunus dulcis</i> cv. Casteltermini skinFood scienceBy-products; Carbohydrate hydrolysing enzymes; GC–MS; LC-ESI/LTQOrbitrap/ MS; Lipase; Prunus dulcis cv. Casteltermini skin; Rubus ulmifolius<i>Rubus ulmifolius</i>by-productsMolecular BiologyLC-ESI/LTQOrbitrap/MSABTSRubus ulmifoliusbiologyChemistryBy-products Carbohydrate hydrolysing enzymes GC–MS LC-ESI/LTQOrbitrap/ MS Lipase Prunus dulcis cv. Casteltermini skin Rubus ulmifoliusfungi010401 analytical chemistryfood and beveragesSettore CHIM/06 - Chimica Organica04 agricultural and veterinary sciencesCell Biologybiology.organism_classification040401 food sciencehumanities0104 chemical sciencesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreePrunus dulcisProanthocyanidinPhytochemicalLC-ESI/LTQOrbitrap/ MSTherapeutics. PharmacologyRubus ulmifoliusAntioxidants
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Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities.

2017

Ruta chalepensis L. (Rutaceae) leaf extract was investigated for its chemical profile and antioxidant and hypoglycaemic properties. The antioxidant effects were investigated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), Chi-carotene bleaching, and metal chelating activity assays. The carbohydrate-hydrolysing enzymes inhibition assay was used to test the hypoglycaemic potential. R. chalepensis showed a high content of hesperidin and rutin with values of 591.9 and 266.7 mg/g dry extract, respectively. The extract exhibited a promising protection of lipid peroxidation (IC50 value of 16.9 mu g/mL) and inhibited both alpha-amylase and alpha-glucosidase enzymes in a concentration-dependent manner. The…

leaveMetal chelating activityAntioxidantDPPHmedicine.medical_treatmentRutinHPLC analysiantioxidant activityPlant Science01 natural sciencesBiochemistryAntioxidantsAnalytical ChemistryLipid peroxidationRutinchemistry.chemical_compoundHesperidinEnzyme InhibitorEnzyme InhibitorsTraditional medicinebiologyHydrolysisbeta CaroteneRuta chalepensisAntioxidantPlant Leavehypoglycaemic activityPlant Extractalpha-AmylaseInhibitory Concentration 50PicratesRuta chalepensiBotanymedicineGlycoside Hydrolase InhibitorsGlycoside Hydrolase InhibitorRutaDose-Response Relationship Drug010405 organic chemistryPlant ExtractsHesperidinOrganic ChemistryBiphenyl CompoundsSettore CHIM/06 - Chimica Organicabiology.organism_classificationHydrolysi0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryRutaceaechemistryBiphenyl CompoundPicrateLipid Peroxidationalpha-AmylasesNatural product research
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Ceiba speciosa (A. St.-Hil.) Seeds Oil: Fatty Acids Profiling by GC-MS and NMR and Bioactivity

2020

This study aimed to evaluate the chemical composition by gas chromatography-mass spectrometry (GC-MS) and Nuclear Magnetic Resonance (NMR) analyses, the antioxidant activities evaluated by different in vitro assays namely 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2&prime

obesityAntioxidantantioxidantDPPHLinoleic acidmedicine.medical_treatmentMalvalic acidPharmaceutical Science01 natural sciencesArticleAnalytical ChemistryPalmitic acidlcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryfixed oilDrug DiscoverymedicineSettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryLipaseChromatographyABTSbiologydiabetesOrganic Chemistry04 agricultural and veterinary sciencesSettore CHIM/06 - Chimica Organicabiology.organism_classification040401 food scienceNMR0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryChemistry (miscellaneous)diabetebiology.proteinMolecular MedicineGC-MSCeiba speciosaMolecules
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Comparative chemical composition and bioactivity of leaves essential oils from nine Sicilian accessions of Myrtus communis L.

2019

In this study, the essential oils obtained from the leaves of Myrtus communis L. stored in a collection orchard located at the experimental station ‘Orleans’ of the Department of Agricultural and Forest Sciences of the University of Palermo (Italy) were investigated. The essential oils, analysed by gas chromatography–mass spectrometry, revealed the presence of α-pinene, 1,8-cineole, linalool, limonene and myrtenyl acetate as dominant constituents. The neuroprotective effects of M. communis essential oils were investigated by analysing the antioxidant properties and cholinesterases (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE) inhibitory activity. Essential oils from Scopello…

leaveMyrtus communis010405 organic chemistrychemical profileantioxidant activityGeneral ChemistryBiology01 natural scienceslanguage.human_language0104 chemical sciencescholinesterase inhibitory activityMyrtus communis010404 medicinal & biomolecular chemistryHorticulturelanguageMyrtus communis L.OrchardChemical compositionSicilianJournal of Essential Oil Research
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Investigating the Antiproliferative and Antioxidant Properties of Pancratium maritimum L. (Amaryllidaceae) Stems, Flowers, Bulbs, and Fruits Extracts

2018

Pancratium maritimumstems, flowers, bulbs, and fruits extracts were investigated for their antiproliferative and antioxidant properties. Total phenols and total flavonoids were also determined. Thein vitroantiproliferative activity was tested against seven cancer cell lines such as C32, HeLa, MDA-MB-231, PC3, A549, MCF-7, and LNCaP by using SRB assay. Interesting results were obtained with stems ethanol extract (ET1) against C32 cells (IC50of 27.1μg/mL) and fruits aqueous extract (AQ) against MCF-7 cell line (IC50of 36.5μg/mL). To define the antioxidant activity, four tests such as DPPH, ABTS FRAP, andβ-carotene bleaching tests were used.The most promising ABTS scavenging capacity was obser…

antioxidantAntioxidantABTSbiologyTraditional medicineArticle SubjectChemistryPancratium maritimumDPPHmedicine.medical_treatment04 agricultural and veterinary sciencesAmaryllidaceaelcsh:Other systems of medicinebiology.organism_classificationlcsh:RZ201-999040401 food scienceHeLachemistry.chemical_compound0404 agricultural biotechnologyComplementary and alternative medicineantiproliferativemedicinePhenolsIC50Pancratium maritimumEvidence-Based Complementary and Alternative Medicine
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High-Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry (HPLC-ESI-MSn) Analysis and Bioactivity Useful for Prevention…

2019

This study aimed at evaluating and comparing the chemical profile obtained by HPLC-ESI-MSn analysis, the inhibitory activity of enzymes linked to obesity (α-amylase, α-glucosidase, and lipase) and the antioxidant properties (DPPH, ABTS, FRAP, and β-carotene bleaching tests) of ethanol extracts of bulbs (BE) and aerial parts (APE) from Allium commutatum Guss. (known in Italy as “aglio delle isole”). The chemical profile revealed alliin as the main abundant compound with values of 31.5 and 38.8 mg/g extract for BE and APE, respectively. APE is rich also in quercetin (38.5 mg/g extract) and luteolin (31.8 mg/g extract). Bulbs extract exhibited the highest activity as inhibitor of enzymes linke…

0301 basic medicineDPPHAllium commutatumElectrospray ionizationBulbsAlliinHigh-performance liquid chromatographyAntioxidantsAllium03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyAntioxidant activityTandem Mass SpectrometryCarbohydrate-hydrolysing enzymes inhibitionEnzyme InhibitorsGarlicChromatography High Pressure Liquid030109 nutrition & dieteticsABTSChromatographybiologyPlant Extracts04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceLipase inhibitionItalychemistryChemistry (miscellaneous)AlliumAerial parts; Antioxidant activity; Bulbs; Carbohydrate-hydrolysing enzymes inhibition; Garlic; Lipase inhibitionAerial partsQuercetinFood SciencePlant Foods for Human Nutrition
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