0000000000356942

AUTHOR

Minna Rusanen

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Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

2013

Abstract Background Physical activity may be beneficial for cognition, but the effect may vary depending on personal characteristics. Methods We investigated the associations between leisure-time physical activity (LTPA) from mid- to late life, the risk of dementia, and the role of body mass index, sex, and APOE in the CAIDE study during 28-year follow-up. Cognitive function of a random subsample was assessed at a mean age of 78.8 years (n = 1511), and dementia/Alzheimer's disease (AD) diagnoses were identified from national registers for the entire target population (n = 3559). Results Moderate (hazard ratio [HR], 1.46; 95% confidence interval [CI], 1.08–1.99) and low levels of midlife LTP…

GerontologyMaleEpidemiologyNeuroimagingOverweightMotor ActivityNeuropsychological TestsCommunity Health PlanningBody Mass IndexCellular and Molecular NeuroscienceLeisure ActivitiesDevelopmental NeuroscienceRisk FactorsmedicineDementiaHumansLongitudinal StudiesObesityExerciseFinlandAgedProportional Hazards Models2. Zero hungerAged 80 and overPsychiatric Status Rating ScalesPhysical activityHealth PolicyHazard ratioAge FactorsLife courseta3142Middle Agedmedicine.diseaseObesityConfidence interval3. Good healthPsychiatry and Mental healthDisease ProgressionLife course approachFemaleDementiaNeurology (clinical)Geriatrics and Gerontologymedicine.symptomPsychologyCohort studyBody mass indexCohort studyAlzheimers and Dementia
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