0000000000359088

AUTHOR

M. S. Abu-darwish

showing 6 related works from this author

Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory do…

2015

Abstract Ethnopharmacologic relevance Artemisia herba-alba Asso (“desert wormwood” in English; “armoise blanche” in French; “shaih” in Arabic), is a medicinal and strongly aromatic plant widely used in traditional medicine by many cultures since ancient times. It is used to treat inflammatory disorders (colds, coughing, bronchitis, diarrhea), infectious diseases (skin diseases, scabies, syphilis) and others (diabetes, neuralgias). In Jordanian traditional medicine, this plant is used as antiseptic and against skin diseases, scabies, syphilis, fever as well as menstrual and nervous disorders. Aim of the study Considering the traditional medicinal uses and the lack of scientific studies addre…

Antifungal AgentsCell Survivalmedicine.drug_classAnti-Inflammatory AgentsBiologyPharmacologyAnti-inflammatorylaw.inventionMiceMinimum inhibitory concentrationCamphorchemistry.chemical_compoundlawDrug DiscoveryOils VolatilemedicineAnimalsPlant OilsViability assayCandida albicansEssential oilPharmacologyJordanDose-Response Relationship DrugTraditional medicineArtemisia herba-albaPlant Components Aerialbiology.organism_classificationArtemisiachemistryArtemisiaJournal of Ethnopharmacology
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Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan

2016

Abstract Ethnopharmacologic relevance Artemisia judaica L. (Arabic name: Beithran ), is a medicinal and aromatic plant growing in the valley bottoms of desert areas, particularly in the southern desert of Jordan nearest to the Jordan-Saudi Arabia borders and in Wadi Araba in the Southern Badia. In Jordan, A. judaica is widely used in traditional medicine being recommended by aboriginal Bedouins in the North Badia region of Jordan as calmative. Furthermore, it is used for the treatment of stomach ache, heart diseases, sexual weakness, diabetes, gastro-intestinal disorders and external wounding. Additionally, other folk medicines of the Arabic region commonly use this aromatic plant for the t…

Lipopolysaccharides0301 basic medicineAntifungal AgentsDPPHAnti-Inflammatory AgentsGerm tube01 natural scienceslaw.inventionMicechemistry.chemical_compoundCamphorlawCandida albicansDrug DiscoveryCandida albicansbiologyTraditional medicineHep G2 CellsCorpus albicansDesert ClimatePiperitoneCell SurvivalMicrobial Sensitivity TestsNitric OxideGas Chromatography-Mass SpectrometryArtemisia judaica03 medical and health sciencesOils VolatileAnimalsHumansPlant OilsEssential oilPharmacologyJordanPlants MedicinalDose-Response Relationship DrugPlant ExtractsMacrophagesMacrophage ActivationPlant Components Aerialbiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistryRAW 264.7 Cells030104 developmental biologyArtemisiachemistryBiofilmsCryptococcus neoformansPhytotherapyJournal of Ethnopharmacology
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Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); chemical characterization and assessment of biological activities

2016

Abstract Ethnopharmacologic relevance Ziziphora tenuior L. (Lamiaceae) is a medicinal plant in Jordan, which is included in various antimicrobial, antiseptic, expectorant and wound healing preparations. It is used for the treatment of cough, stomach ache, dysentery, fever, uterus infection, gut inflammation and painful menstruation. Aim of the study The aim of this study was to assess, for the first time, the chemical composition of the essential oil of Z. tenuior originated from southern Jordan and its antifungal effects against several yeasts. Concomitantly, the mechanisms behind the anti-fungal activity against Candida albicans were also disclosed. Since the Z. tenuior traditional uses a…

0301 basic medicineAntifungal Agents030106 microbiologyAnti-Inflammatory AgentsGerm tubeCyclohexane MonoterpenesMicrobial Sensitivity Tests[SDV.BID]Life Sciences [q-bio]/Biodiversity01 natural sciencesCell Linelaw.inventionMicrobiologyMice03 medical and health scienceschemistry.chemical_compoundlawCell Line TumorCandida albicansDrug DiscoveryOils VolatileAnimalsHumansPlant OilsBiomassCandida albicansEssential oilComputingMilieux_MISCELLANEOUSPharmacologyJordanLamiaceaebiologyTerpenesMacrophagesBiological activityHep G2 Cellsbiology.organism_classificationAntimicrobialCorpus albicans3. Good health0104 chemical sciences010404 medicinal & biomolecular chemistryAspergilluschemistryCryptococcus neoformansMonoterpenesLamiaceaePulegone
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Biopiracy of natural products and good bioprospecting practice

2016

Made available in DSpace on 2018-11-26T16:27:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-02-15 Deutsche Forschungsgemeinschaft Background: Biopiracy mainly focuses on the use of biological resources and/or knowledge of indigenous tribes or communities without allowing them to share the revenues generated out of economic exploitation or other non-monetary incentives associated with the resource/knowledge. Methods: Based on collaborations of scientists from five continents, we have created a communication platform to discuss not only scientific topics, but also more general issues with social relevance. This platform was termed 'PhytCancer -Phytotherapy to Fight Cancer' (www.phy…

0301 basic medicineResource (biology)Drug IndustryInternational CooperationTheftPharmaceutical ScienceIntellectual property0603 philosophy ethics and religionIndigenousPatents as Topic03 medical and health sciencesIndigenous knowledgeDrug DiscoveryPatents as TopicTraditional knowledgeDeveloping CountriesPharmacologyBioprospectingBiological ProductsBioprospectingPlants Medicinalbusiness.industryIntellectual propertyCommercializationOwnership06 humanities and the artsPublic relationsBioethicsNatural resource030104 developmental biologyIncentiveComplementary and alternative medicineEthnopharmacologyMolecular MedicinePatent060301 applied ethicsBusiness
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Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants

2017

Abstract Background Monoamine oxidases (MAOs) are outer mitochondrial membrane flavoenzymes. They catalyze the oxidative deamination of a variety of neurotransmitters. MAO-A and MAO-B may be considered as targets for inhibitors to treat neurodegenerative diseases and depression and for managing symptoms associated with Parkinson's and Alzheimer's diseases. Purpose The objective was to evaluate the inhibitory effect of Hypericum afrum and Cytisus villosus against MAO-A and B and to isolate the compounds responsible for the MAO-inhibitory activity. Methods The inhibitory effect of extracts and purified constituents of H. afrum and C. villosus were investigated in vitro using recombinant human…

0301 basic medicineMonoamine Oxidase InhibitorsMonoamine oxidaseDrug Evaluation PreclinicalPharmaceutical ScienceGenisteinMixed inhibitionArticleMass SpectrometryInhibitory Concentration 5003 medical and health scienceschemistry.chemical_compoundDrug DiscoveryHumansChrysinMonoamine OxidaseIC50CytisusFlavonoidsPharmacologyPlants MedicinalMolecular Docking Simulation030104 developmental biologyComplementary and alternative medicinechemistryBiochemistryDocking (molecular)AlgeriaMolecular MedicineQuercetinMyricetinQuercetinHypericumPhytomedicine
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Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts.

2017

Abstract Background Practices of biopiracy to use genetic resources and indigenous knowledge by Western companies without benefit-sharing of those, who generated the traditional knowledge, can be understood as form of neocolonialism. Hypothesis The One-World Medicine concept attempts to merge the best of traditional medicine from developing countries and conventional Western medicine for the sake of patients around the globe. Study design Based on literature searches in several databases, a concept paper has been written. Legislative initiatives of the United Nations culminated in the Nagoya protocol aim to protect traditional knowledge and regulate benefit-sharing with indigenous communiti…

Complementary TherapiesQuality ControlInternational CooperationPopulationPharmaceutical ScienceTheftLegislationSelf MedicationColonialismIndigenousPatents as Topic03 medical and health sciences0302 clinical medicineDouble-Blind MethodPolitical scienceDrug DiscoveryHealth careHumansNagoya ProtocolEuropean UnionTraditional knowledgeeducationDeveloping Countries030304 developmental biologyPharmacology0303 health scienceseducation.field_of_studyEvidence-Based MedicinePlants Medicinalbusiness.industryEvidence-based medicineBiodiversityPublic relationsComplementary and alternative medicine030220 oncology & carcinogenesisNaturopathyMolecular MedicineIntegrative medicineMedicine TraditionalbusinessPhytomedicine : international journal of phytotherapy and phytopharmacology
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