0000000000360085

AUTHOR

B. Gomila

showing 2 related works from this author

Is there a widespread clone of Serratia marcescens producing outbreaks worldwide?

2021

[Background]: Serratia marcescens frequently causes outbreaks in healthcare settings. There are few studies using high-throughput sequencing (HTS) that analyse S. marcescens outbreaks. We present the analysis of two outbreaks in neonatal intensive care units (NICUs) in hospitals from the Comunitat Valenciana (CV, Spain) and the impact of using different reference genomes.

Microbiology (medical)clone (Java method)Mapping referenceMicrobial Sensitivity Tests030501 epidemiologyGenomeDNA sequencingNICU outbreaksDisease OutbreaksSerratia Infections03 medical and health sciencesIntensive Care Units NeonatalIntensive careHumansMedicineSerratia marcescensGeneticsCross Infection0303 health sciencesHigh-throughput sequencingbiology030306 microbiologybusiness.industryStrain (biology)Infant NewbornOutbreakGeneral Medicinebiology.organism_classificationClone CellsInfectious DiseasesSpainHealthcare settingsSerratia marcescens0305 other medical sciencebusinessNosocomial outbreaks
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Unexpected postmortem diagnosis of Acanthamoeba meningoencephalitis following allogeneic peripheral blood stem cell transplantation.

2008

Meningoencephalitis caused by pathogenic free-living amebas is usually fatal. Only a few cases of Acanthamoeba meningoencephalitis, diagnosed at autopsy, have been reported following hematopoietic stem cell transplantation. We here report a case of Acanthamoeba meningoencephalitis following allogeneic peripheral blood stem cell transplantation with rapidly evolving neurologic symptoms that remained unexplained. Magnetic resonance imaging failed to show brain lesions and cerebrospinal fluid was negative for microbiological cultures. Definite diagnosis was an unexpected autopsy finding. As overall and teaching hospital autopsy rates are declining worldwide, we must emphasize the need of autop…

Pathologymedicine.medical_specialtymedicine.medical_treatmentAcanthamoebaAutopsyHematopoietic stem cell transplantationCentral nervous system diseaseCerebrospinal fluidMeningoencephalitismedicineAnimalsHumansImmunology and AllergyPharmacology (medical)Postmortem DiagnosisPeripheral Blood Stem Cell TransplantationTransplantationbiologybusiness.industryMeningoencephalitisAmebiasismedicine.diseasebiology.organism_classificationAcanthamoebaStem cellbusiness
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