0000000000362243

AUTHOR

Carmelo González

showing 2 related works from this author

Diagnostic significance of SARS-CoV-2 IgM positive/IgG negative antibody profile in symptomatic patients with suspected COVID-19 testing negative by …

2020

An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time RT-PCR. However, the false-negative rate of the technique is unneglectable and serological methods are urgently warranted. Here, we presented the colloidal gold-based immunochromatographic (ICG) strip targeting viral IgM or IgG antibody and compared it with real-time RT-PCR. The sensitivity of ICG assay with IgM and IgG combinatorial detection in nucleic acid confirmed cases were 11.1%, 92.9% and 96.8% at the early stage (1-7 days after onset), intermediate stage (8-14 …

AdultMaleMicrobiology (medical)2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralNegative antibodyReal-Time Polymerase Chain ReactionAntibodies ViralArticleImmunoglobulin GBetacoronavirusYoung AdultCOVID-19 TestingHumansMedicineSerologic Testsskin and connective tissue diseasesPandemicsAgedAged 80 and overImmunoassaybiologyReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2business.industryfungiCOVID-19Middle AgedVirologybody regionsInfectious DiseasesReal-time polymerase chain reactionImmunoglobulin MImmunoglobulin MImmunoglobulin Gbiology.proteinFemaleAntibodyCoronavirus InfectionsbusinessJournal of Infection
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Caveats in interpreting SARS‐CoV‐2 IgM + /IgG − antibody profile in asymptomatic health care workers

2020

Serological testing is increasingly recognized as a useful tool for management of the COVID‐19 pandemic.1 Cross‐sectional serosurveys provide information on exposure levels in a target population, which is helpful for designing public health strategies to blunt community transmission.2 This article is protected by copyright. All rights reserved.

medicine.medical_specialty2019-20 coronavirus outbreakbusiness.industryPublic healthSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Target populationAsymptomaticVirology03 medical and health sciences0302 clinical medicineInfectious DiseasesAntibody ProfileVirologyHealth caremedicine030211 gastroenterology & hepatology030212 general & internal medicinemedicine.symptomSeroconversionbusinessIntensive care medicineJournal of Medical Virology
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