0000000000362341
AUTHOR
Magda Monari
Ru(bpy)2Cl2: A catalyst able to shift the course of the photorearrangement in the Boulton-Katritzky reaction
The Boulton-Katritzky reaction represents one of the most popular and efficient strategies used to realize azole-into-azole conversions. For example, under different experimental conditions, it allows the rearrangement of Z-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazoles (1) into 2-aryl-4-benzoylamino-5-phenyl-2H-1,2,3-triazoles (2) in very high yields. Moreover, we have recently realized this conversion also by UV-photostimulation. Now we have enlarged the scope of the reaction irradiating with visible or UV light an acetonitrile solution of some Z-arylhydrazones (1a-e) in the presence of catalytic amounts of Ru(bpY)(2)Cl-2. We have observed the unexpected formation of the 1-aryl-5-…
Pentamethylcyclopentadienyl-rhodium and iridium complexes containing (N^N and N^O) bound chloroquine analogue ligands: synthesis, characterization and antimalarial properties
The synthesis and characterization of twenty new pentamethylcyclopentadienyl-rhodium and iridium complexes containing N^N and N^O-chelating chloroquine analogue ligands are described. The in vitro antimalarial activity of the new ligands as well as the complexes was evaluated against the chloroquine sensitive (CQS) NF54 and the chloroquine resistant (CQR) Dd2 strains of Plasmodium falciparum. The antimalarial activity was found to be good to moderate; although all complexes are less active than artesunate, some of the ligands and complexes showed better activity than chloroquine (CQ). In particular, rhodium complexes were found to be considerably more active than iridium complexes against t…
ChemInform Abstract: Ru(bpy)2Cl2: A Catalyst Able to Shift the Course of the Photorearrangement in the Boulton-Katritzky Reaction.
Abstract The Boulton–Katritzky reaction represents one of the most popular and efficient strategies used to realize azole-into-azole conversions. For example, under different experimental conditions, it allows the rearrangement of Z-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazoles (1) into 2-aryl-4-benzoylamino-5-phenyl-2H-1,2,3-triazoles (2) in very high yields. Moreover, we have recently realized this conversion also by UV-photostimulation. Now we have enlarged the scope of the reaction irradiating with visible or UV light an acetonitrile solution of some Z-arylhydrazones (1a–e) in the presence of catalytic amounts of Ru(bpy)2Cl2. We have observed the unexpected formation of the 1-a…
CCDC 1426907: Experimental Crystal Structure Determination
Related Article: Erik Ekengard, Kamlesh Kumar, Thibault Fogeron, Carmen de Kock, Peter J. Smith, Matti Haukka, Magda Monari, Ebbe Nordlander|2016|Dalton Trans.|45|3905|doi:10.1039/C5DT03739E
CCDC 1426908: Experimental Crystal Structure Determination
Related Article: Erik Ekengard, Kamlesh Kumar, Thibault Fogeron, Carmen de Kock, Peter J. Smith, Matti Haukka, Magda Monari, Ebbe Nordlander|2016|Dalton Trans.|45|3905|doi:10.1039/C5DT03739E
CCDC 1426906: Experimental Crystal Structure Determination
Related Article: Erik Ekengard, Kamlesh Kumar, Thibault Fogeron, Carmen de Kock, Peter J. Smith, Matti Haukka, Magda Monari, Ebbe Nordlander|2016|Dalton Trans.|45|3905|doi:10.1039/C5DT03739E
CCDC 1029103: Experimental Crystal Structure Determination
Related Article: Maurizio D’Auria, Vincenzo Frenna, Magda Monari, Antonio Palumbo-Piccionello, Rocco Racioppi, Domenico Spinelli, Licia Viggiani|2015|Tetrahedron Lett.|56|6598|doi:10.1016/j.tetlet.2015.10.030