0000000000362454

AUTHOR

T. K. Held

showing 3 related works from this author

Mycobacterial Infection: A Difficult and Late Diagnosis in Stem Cell Transplant Recipients

2004

The Infectious Diseases Working Party of the European Blood and Marrow Transplant Group conducted a survey to obtain information about the frequency, presentation, and treatment of mycobacterial infection (MBI) in stem cell transplant (SCT) recipients. Among 29 centers, MBI was diagnosed in 0.79% of 1513 allogeneic and 0.23% of 3012 autologous SCT recipients during 1994-1998 a median of 160 days after transplantation. The mean interval between first symptoms and diagnosis was 29 days and was still longer for patients with atypical MBI or recipients of corticosteroid therapy. The prevalence of MBI was highest among those who received matched unrelated or mismatched STCs from related donors. …

AdultMaleMicrobiology (medical)medicine.medical_specialtyTuberculosisAdolescentmedicine.drug_classmedicine.medical_treatmentHematopoietic stem cell transplantationOpportunistic InfectionsInternal medicineEpidemiologymedicineHumansTuberculosisChildRetrospective StudiesMycobacterium Infectionsbusiness.industryIncidenceHematopoietic Stem Cell TransplantationMiddle Agedmedicine.diseaseSurgeryTransplantationsurgical procedures operativeInfectious Diseasesmedicine.anatomical_structureLate diagnosisChild PreschoolCorticosteroidFemaleBone marrowStem cellbusinessStem Cell TransplantationClinical Infectious Diseases
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Toxoplasmosis after hematopoietic stem cell transplantation.

2000

In immunocompromised individuals, toxoplasmosis mostly occurs as a reactivation of a latent infection, causing severe to life-threatening disease. Thus, recipients who are seropositive for Toxoplasma gondii before an allogeneic hematopoietic stem cell transplant (HCT) are at highest risk, although primary infections may also cause severe toxoplasmosis. The disease most often affects the central nervous system, but in HCT recipients other organs are involved in more than half of the cases. Because of the alteration of the immune response in these patients, serodiagnosis is not sufficiently reliable in the diagnosis of post-HCT toxoplasmosis, and direct detection of the causative agent is req…

Microbiology (medical)AdultMaleAdolescentmedicine.medical_treatmentAntiprotozoal AgentsSulfadiazineHematopoietic stem cell transplantationDiseasePharmacotherapyImmunopathologyTrimethoprim Sulfamethoxazole Drug CombinationmedicineAnimalsHumansChildSurvival ratebiologybusiness.industryClindamycinHematopoietic Stem Cell TransplantationToxoplasma gondiiMiddle Agedmedicine.diseasebiology.organism_classificationToxoplasmosisTransplantationSurvival RateInfectious DiseasesPyrimethamineImmunologyDrug Therapy CombinationFemaleAutopsybusinessToxoplasmaToxoplasmosisClinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Toxoplasmosis after hematopoietic stem transplantation. Report of a 5-year survey from the Infectious Diseases Working Party of the European Group fo…

2000

Toxoplasmosis after hematopoietic stem transplantation. Report of a 5-year survey from the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation

medicine.medical_specialtyBone marrow transplantPremedicationAntibodies ProtozoanBlood DonorsOpportunistic InfectionsImmunocompromised HostSeroepidemiologic StudiesInternal medicineTrimethoprim Sulfamethoxazole Drug CombinationEpidemiologymedicineAnimalsHumansTransplantation HomologousTransplantationMarrow transplantationbusiness.industryHematopoietic Stem Cell TransplantationHematologymedicine.diseaseToxoplasmosisTransplantationHaematopoiesissurgical procedures operativeImmunologybusinessToxoplasmaDisease transmissionToxoplasmosisBone Marrow Transplantation
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