0000000000363885

AUTHOR

Giuseppe Renda

showing 16 related works from this author

In Vitro Bioactivity of Astaxanthin and Peptides from Hydrolisates of Shrimp (Parapenaeus longirostris) By-Products: From the Extraction Process to B…

2021

Non-edible parts of crustaceans could be a rich source of valuable bioactive compounds such as the carotenoid astaxanthin and peptides, which have well-recognized beneficial effects. These compounds are widely used in nutraceuticals and pharmaceuticals, and their market is rapidly growing, suggesting the need to find alternative sources. The aim of this work was to set up a pilot-scale protocol for the reutilization of by-products of processed shrimp, in order to address the utilization of this valuable biomass for nutraceutical and pharmaceuticals application, through the extraction of astaxanthin-enriched oil and antioxidant-rich protein hydrolysates. Astaxanthin (AST) was obtained using …

Fish ProteinsFood Handlingantioxidant activityPharmaceutical ScienceAngiotensin-Converting Enzyme InhibitorsPilot ProjectsXanthophyllsfish oilArticleAntioxidantsMicechemistry.chemical_compoundNutraceuticalPenaeidaeprotein hydrolysatesAstaxanthinDrug Discoveryshrimp by-productsAnimalsHumansFood sciencelcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)ShellfishWaste Productschemistry.chemical_classificationHydrolysisExtraction (chemistry)Proteolytic enzymesSupercritical fluid extractionFatty acidChromatography Supercritical FluidGreen Chemistry Technology3T3 Cellsproteolytic enzymesFibroblastsShrimpastaxanthinOxidative Stresslcsh:Biology (General)chemistrySPDsupercritical fluid extractionRabbitsPeptidesPUFAPolyunsaturated fatty acidMarine Drugs
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Biotechnological Applications for the Sustainable Use of Marine By-products: In Vitro Antioxidant and Pro-apoptotic Effects of Astaxanthin Extracted …

2019

In this study, the carotenoid astaxanthin was obtained by supercritical fluid extraction (SFE) from shrimp by-products (SBP). Its bioactive properties were evaluated in vitro in human normal and cancerous cells lines. The antioxidant activity of the extracted astaxanthin of the SFE fraction (ASTA) was tested in fibroblast cells (HS-68), by inducing oxidative stress and by evaluating the protective effect of the pre-treatment with different levels of ASTA against toxicity. The anti-proliferative activity was evaluated in hepatoma cells (HEP-G2), treated with increased concentrations of ASTA and measuring the effects on vitality and on some biomolecular markers related to oxidative stress, ce…

0106 biological sciences0301 basic medicineMarine bioactive compoundAntioxidantmedicine.medical_treatmentBiologymedicine.disease_causeSupercritical fluid extraction01 natural sciencesApplied Microbiology and Biotechnology03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - ZoocoltureAstaxanthin010608 biotechnologymedicineFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaCarotenoidchemistry.chemical_classificationAnti-proliferativeAstaxanthinApoptosiMarine bioactive compounds Astaxanthin Supercritical fluid extraction Antioxidants Anti-proliferative Apoptosis030104 developmental biologychemistryCell cultureApoptosisToxicityAntioxidantOxidative stressMarine Biotechnology
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Effects of BDE-47 exposure on immune-related parameters of Mytilus galloprovincialis.

2019

Abstract The persistent pollutants polybrominated diphenyl ethers (PBDEs) have been demonstrated to produce several negative effects on marine organisms. Although Mytilus galloprovincialis was extensively studied as model system, the effects of PBDEs on the innate immune system of mussels remains unclear. In this study, except for the control treatment, specimens of M. galloprovincialis were fed with microalgae treated with increasing concentrations of PBDEs (maximum level 100 ng L−1 of BDE-47 per day). BDE-47 treatment was maintained for 15 days and then the animals were fed with the same control diet, without contaminants, for 15 days. Samples of haemolymph (HL) were obtained at T0, T15 a…

BivalvesHemocytesHealth Toxicology and MutagenesisPhysiology010501 environmental sciencesAquatic ScienceBactericidal activity01 natural sciences03 medical and health scienceschemistry.chemical_compoundPolybrominated diphenyl ethersImmune systemImmunitySettore AGR/20 - ZoocoltureHemolymphHemolymphHalogenated Diphenyl EthersMicroalgaeAnimalsSettore BIO/06 - Anatomia Comparata E Citologia030304 developmental biology0105 earth and related environmental sciencesPollutantPolybrominated Bivalves Innate immune system Bactericidal activity Haemocytes HaemolymphMytilus0303 health sciencesInnate immune systemHaemocytesbiologyChemistryInnate immune systemBivalveHaemocyteEnvironmental ExposureFeeding BehaviorIntracellular Membranesbiology.organism_classificationSurvival AnalysisMytilusAnti-Bacterial AgentsHaemolymphLysozymeLysosomesPolybrominatedWater Pollutants ChemicalPeptide HydrolasesAquatic toxicology (Amsterdam, Netherlands)
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Culture Conditions Affect Antioxidant Production, Metabolism and Related Biomarkers of the Microalgae Phaeodactylum tricornutum

2022

Phaeodactylum tricornutum (Bacillariophyta) is a worldwide-distributed diatom with the ability to adapt and survive in different environmental habitats and nutrient-limited conditions. In this research, we investigated the growth performance, the total lipids productivity, the major categories of fatty acids, and the antioxidant content in P. tricornutum subjected for 15 days to nitrogen deprivation (N−) compared to standard culture conditions (N+). Furthermore, genes and pathways related to lipid biosynthesis (i.e., glucose-6-phosphate dehydrogenase, acetyl-coenzyme A carboxylase, citrate synthase, and isocitrate dehydrogenase) and photosynthetic activity (i.e., ribulose-1,5-bisphosp…

2. Zero hungerphotosynthesisPhysiologyClinical Biochemistrylipid biosynthesisantioxidant activityCell Biologynitrogen stresslipid biosynthesiBiochemistryPhaeodactylum tricornutumAntioxidantsphotosynthesiAlguesSettore AGR/20 - Zoocolturenitrogen stregene expressionSettore BIO/06 - Anatomia Comparata E CitologiaMolecular Biology<i>Phaeodactylum tricornutum</i>; nitrogen stress; gene expression; lipid biosynthesis; photosynthesis; antioxidant activity
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From Ecology to Biotechnology, Study of the Defense Strategies of Algae and Halophytes (from Trapani Saltworks, NW Sicily) with a Focus on Antioxidan…

2019

This study aimed at the characterization of the antioxidant power of polyphenol extracts (PE) obtained from the algae Cystoseira foeniculacea (CYS) (Phaeophyta) and from the halophyte Halocnemum strobilaceum (HAL), growing in the solar saltworks of western Sicily (Italy), and at the evaluation of their anti-microfouling properties, in order to correlate these activities to defense strategies in extreme environmental conditions. The antioxidant properties were assessed in the PE based on the total antioxidant activity test and the reducing power test

0301 basic medicineDPPH[CHIM.THER]Chemical Sciences/Medicinal Chemistry<i>Cystoseira foeniculacea</i>010501 environmental sciences01 natural sciencesAntioxidantsAnti-oxidantlcsh:Chemistrychemistry.chemical_compoundcrude extractsMarine bacteriophageAnti-Infective Agentslipid oxidationbiodimarCystoseira foeniculacea<i>Halocnemum strobilaceum</i>brown algaFood scienceGallic acidSicilylcsh:QH301-705.5SpectroscopyEcologybiologyanti-microbialmarine-bacteriaantifoulingHalocnemum strobilaceumSalt-Tolerant PlantsGeneral MedicineClosteriumComputer Science Applicationsseaweedscystoseiraradical-scavenging activityBiotechnologyMicrobial Sensitivity TestsPhaeophytaArticleCatalysisInorganic Chemistry03 medical and health sciencesantifouling activitiesPicratesAlgaeLipid oxidationDefense14. Life underwaterPhysical and Theoretical ChemistryMolecular BiologyShellfishpolyphenols0105 earth and related environmental sciencesBacteriaACLBiphenyl CompoundsOrganic Chemistrybiology.organism_classificationdefenses030104 developmental biologychemistrylcsh:Biology (General)lcsh:QD1-99913. Climate actionPolyphenolanti-oxidantsseasonal-variation[SDE.BE]Environmental Sciences/Biodiversity and Ecologyphenolic compositionInternational Journal of Molecular Sciences
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Farmed Gilthead Sea Bream (Sparus aurata) by-Products Valorization: Viscera Oil ω-3 Enrichment by Short-Path Distillation and In Vitro Bioactivity Ev…

2021

This study shows a pilot scale protocol aimed to obtain an omega 3-enriched oil after the processing of farmed gilthead sea bream viscera (SBV)

Antioxidant030309 nutrition & dieteticsThiobarbituric acidFish farmingmedicine.medical_treatmentShort path distillationPharmaceutical SciencePilot ProjectsnutraceuticsAntioxidantsMice03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologySettore AGR/20 - Zoocolture3T3-L1 CellsFatty Acids Omega-3Drug DiscoveryAdipocytesTBARSmedicineAnimalsPeroxide valueFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaPharmacology Toxicology and Pharmaceutics (miscellaneous)by-productslcsh:QH301-705.5DistillationWaste Productschemistry.chemical_classification0303 health sciencesAdipogenesisomega-3 fatty acidsFatty acid04 agricultural and veterinary sciences040401 food scienceSea Breamfish oilsOxidative StressViscerachemistryaquaculturelcsh:Biology (General)BassPolyunsaturated fatty acidMarine Drugs
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Effect of natural antioxidants and modified atmosphere packaging in preventing lipid oxidation and increasing the shelf-life of common dolphinfish (C…

2015

We investigated the effects of natural antioxidants and modified atmosphere packaging (MAP) on the quality and shelf-life of Coryphaena hippurus (common dolphinfish) fillets. Fillets of the control group (CO) were simply placed on trays and not sealed. Fillets of the second group (MAP) were preserved in modified atmosphere (45% CO2, 50% N2, 5% O2), and fillets of the third group (MAP-AOX) were preserved by combining natural antioxidants from halophytes with modified atmosphere. All samples were stored in a refrigerator at 1 ± 0.5 C for 18 days. Analyses were conducted at T0 and after 3, 6, 12, 15 and 18 days of storage. According to sensory tests and colour analyses, the fillets in the MAP …

chemistry.chemical_classificationCoryphaenaAntioxidantbiologyChemistrymedicine.medical_treatmentCommon dolphinfish Antioxidant Modified atmosphere packaging Lipid oxidation Shelf-lifeShelf lifebiology.organism_classificationBiochemistryLipid oxidationSensory testsSettore AGR/20 - ZoocoltureModified atmospheremedicineFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaFood SciencePolyunsaturated fatty acidLWT - Food Science and Technology
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Antioxidant Properties of a Supercritical Fluid Extract of the Halophyte Mesembryanthemum nodiflorum L. from Sicilian Coasts: Nutraceutical and Cosme…

2020

The aim of this paper was to obtain different extracts from the aerial parts of Mesembryanthemum nodiflorum, comparing traditional extraction (using solvents with increasing polarity such as hexane, ethanol 80%, acetone 70% and water) with an eco-friendly technique (supercritical fluid extraction (SFE))

AntioxidantantioxidantDPPHmedicine.medical_treatmentice plant01 natural sciencesSFEIntegrin 1lcsh:Technologylcsh:Chemistry03 medical and health scienceschemistry.chemical_compoundNutraceuticalSettore AGR/20 - Zoocolturemedicineoxidative stressGeneral Materials ScienceMesembryanthemum nodiflorumFood scienceInstrumentationlcsh:QH301-705.5030304 developmental biologyFluid Flow and Transfer Processes0303 health sciencescell cultureSirt1biologyChemistrylcsh:TProcess Chemistry and TechnologyExtraction (chemistry)General EngineeringSupercritical fluid extractionIntegrin α1biology.organism_classificationlcsh:QC1-9990104 chemical sciencesComputer Science Applications010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999Polyphenollcsh:TA1-2040Oxidative strelcsh:Engineering (General). Civil engineering (General)Cosmeceuticallcsh:PhysicsApplied Sciences
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Tunisian tomato by-products, as a potential source of natural bioactive compounds.

2016

Consumption of tomato and tomato products is positively related to the reduction in cardiovascular disease and several types of cancer, thanks to the presence of natural compounds, such as antioxidants. Peels and seeds fractions of tomato, collected after industrial processing in Tunisian industries, were analysed for nutritional and antioxidants composition in perspective of its utilisation. Proximate composition, fatty acids profile, carotenoids, such as lycopene and beta-carotene, polyphenols contents, demonstrated the good potential of these residual products as a source of natural compounds, useful for food and nutraceuticals applications.

antioxidantTunisiaFood Handling020209 energy02 engineering and technologyPlant ScienceBiochemistryAntioxidantsAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyNutraceuticalLycopeneSolanum lycopersicumPicratesSettore BIO/10 - BiochimicaBotany0202 electrical engineering electronic engineering information engineeringFood IndustryPotential sourceFood scienceCarotenoidchemistry.chemical_classificationBiological ProductsMedicine (all)Organic ChemistryBiphenyl CompoundsFatty Acidsfood and beveragesPolyphenolsSettore AGR/15 - Scienze E Tecnologie Alimentari04 agricultural and veterinary sciencesFree Radical ScavengersTomato productsProximate composition040401 food scienceCarotenoidscarotenoidLycopenepolyphenolchemistryPolyphenolFruitSeedsComposition (visual arts)fatty acidNatural product research
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Antioxidant Bioactivity of Extracts from Beach Cast Leaves of Posidonia oceanica (L.) Delile

2021

The marine environment is a generous source of biologically active compounds useful for human health. In 50 years, about 25,000 bioactive marine compounds have been identified, with an increase of 5% per year. Peculiar feature of algae and plants is the production of secondary metabolites, such as polyphenols, synthesized as a form of adaptation to environmental stress. Posidonia oceanica is a Mediterranean endemic and dominant seagrass and represents a biologically, ecologically and geologically important marine ecosystem. Within this study, methanolic and ethanolic extracts were generated from fresh and dried Posidonia&nbsp

AntioxidantDPPHQH301-705.5medicine.medical_treatmentPharmaceutical Science<i>Posidonia oceanica</i>medicine.disease_cause01 natural sciences03 medical and health scienceschemistry.chemical_compoundAlgaephoto protectionSettore AGR/20 - ZoocoltureDrug Discoverymedicineoxidative stress14. Life underwaterFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaBiology (General)Pharmacology Toxicology and Pharmaceutics (miscellaneous)polyphenols030304 developmental biology0303 health sciencesbiologyChemistry010401 analytical chemistryPosidonia oceanicaBiological activitybiology.organism_classification0104 chemical sciencesSeagrassantioxidants13. Climate actionPolyphenolPosidonia oceanicaOxidative stressMarine Drugs
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The Inclusion of a Supercritical Fluid Extract, Obtained From Honey Bee Pollen, in the Diet of Gilthead Sea Bream (Sparus aurata), Improves Fish Immu…

2020

In the present study, the immune-stimulatory effect of two levels of honey bee pollen (5 and 10%, P5 and P10 treatment, respectively) and its supercritical fluid extract (0. 5 and 1%, E0.5 and E1, respectively) included in the diet, was tested in gilthead seabream (Sparus aurata). The in vivo trial was preceded by the evaluation of antioxidant properties of three different bee pollen extracts obtained by water, ethanol 80%, and Supercritic Fluids Extraction (SFE). The preliminary evaluation attested that the SFE showed the lowest extraction yield (10.47%) compared to ethanol 80% (48.61%) and water (45.99%). SFE extract showed good antioxidant properties with high polyphenol content (13.06 m…

Antioxidantmedicine.medical_treatmenthoney bee pollen supercritical fluid extraction antioxidants immune-stimulation Sparus auratamedicine.disease_causechemistry.chemical_compoundSettore AGR/20 - ZoocoltureSparus aurataPollenmedicineFood scienceimmune-stimulationEC50Original Researchlcsh:Veterinary medicineGeneral VeterinaryChemistrySupercritical fluid extractionfood and beveragesHoney beeantioxidantsPolyphenolBee pollenlcsh:SF600-1100Veterinary Sciencesupercritical fluid extractionLysozymehoney bee pollenFrontiers in Veterinary Science
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Species-Specific Antioxidant Power and Bioactive Properties of the Extracts Obtained from Wild Mediterranean Calendula Spp. (Asteraceae)

2019

In this study we focused on four taxa of the genus Calendula (C. maritima, C. suffruticosa subsp. fulgida, C. arvensis, and the hybrid between the first two ones), collected in Mediterranean area (Sicily). Six extracts for each species were obtained using solvents with increasing polarity (hexane, ethanol 80%, acetone 70%, and water) and through extraction by supercritical fluids (SFE). It has been observed that the solvent with the highest extraction efficiency was ethanol 80% for all species. However, SFE extracts showed high antioxidant activity comparable to the ethanol 80% extract (polyphenol, DPPH, and reducing power method). These findings were confirmed by in vitro analysis (MTT ass…

antioxidantAntioxidantDPPHmedicine.medical_treatmentcalendula specielcsh:Technology01 natural scienceslcsh:Chemistrystresschemistry.chemical_compoundSettore BIO/10 - BiochimicaGeneral Materials ScienceFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaCalendulalcsh:QH301-705.5InstrumentationFluid Flow and Transfer Processes0303 health sciencesbiologyplantsGeneral EngineeringSupercritical fluid extractionlcsh:QC1-999Computer Science ApplicationsSolventantioxidantscalendula speciesopuntia-ficus-indica03 medical and health sciencesmedicineAcetoneby-productspolyphenols030304 developmental biologylcsh:TACLProcess Chemistry and TechnologyExtraction (chemistry)assaybiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999chemistrylcsh:TA1-2040PolyphenolbioactivitySettore BIO/03 - Botanica Ambientale E Applicataflavonoidsmarigoldsupercritical fluid extraction[SDE.BE]Environmental Sciences/Biodiversity and Ecologylcsh:Engineering (General). Civil engineering (General)lcsh:Physicsphenolic compositionApplied Sciences
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Diversification de la production de l’aquaculture sicilienne à travers la production de filets de maigre (Argyrosmus regius) fumés: de la caractérisa…

2016

Within the Work-package 5 «Valorisation de l'image des produits aquacoles», activity 5.3 «Innovation en vue de valoriser les produits aquacoles», a cold smoking protocol was applied on meagre, Argyrosomus regius fillets, an emerging species for Sicilian aquaculture. Nutritional characterization and consumer tests were conducted on three different scales (laboratory, restaurant, seafood exhibition), in order to record the level of consumers’ satisfaction towards this new product. The results obtained indicate that the applied cold smoking protocol yielded a product with nutritional value comparable to fresh fillets. The low level of lipids and the high content of polyunsaturated fatty acids …

aquacultureSettore AGR/20 - ZoocoltureArgirosomus regiusfish qualityinnovationcold smoking
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Valorization of Side Stream Products from Sea Cage Fattened Bluefin Tuna (Thunnus thynnus): Production and In Vitro Bioactivity Evaluation of Enriche…

2022

The valorization of side streams from fishery and aquaculture value-chains is a valuable solution to address one of the challenges of the circular economy: turning wastes into profit. Side streams produced after filleting of sea cage fattened bluefin tuna (Thunnus thynnus) were analyzed for proximate composition and fatty acid profile to evaluate the possibility of producing tuna oil (TO) as a valuable source of &omega;-3 polyunsaturated fatty acids (PUFA) and testing its bioactivity in vitro. Ethyl esters of total fatty acids (TFA), obtained from TO, were pre-enriched by urea complexation (PUFA-Ue) and then enriched by short path distillation (SPD) up to almost 85% of the PUFA fraction (PU…

side streamsfood and beveragesbiomarkersPharmaceutical Scienceω-3 fatty acidseye diseasesadipogenesisSAF-1 cell lineSettore AGR/20 - Zoocoltureside streams; ω-3 fatty acids; tuna fish oils; SAF-1 cell line; biomarkers; lipid metabolism; adipogenesislipid metabolismDrug Discoverylipids (amino acids peptides and proteins)Settore BIO/06 - Anatomia Comparata E Citologiahuman activitiesPharmacology Toxicology and Pharmaceutics (miscellaneous)tuna fish oilsMarine Drugs
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By-products of farmed European sea bass (Dicentrarchus labrax L.) as a potential source of n-3 PUFA

2013

Total by-products (TBP) obtained by filleting farmed and wild European sea bass (Dicentrarchus labrax) were analyzed to evaluate if, on the basis of the percentage yield, total lipid content and fatty acid composition, they can be considered a resource of n-3 polyunsaturated fatty acids (PUFA). Results show that TBP from intensively farmed fish (IFF) contain higher total lipid content and have a higher level of n-3 PUFA rich in eicosapentaenoic (EPA) and docosaexaenoic acid (DHA), compared to extensively farmed fish (EFF) and to wild fish (WF) (P < 0.05). This difference may suggest a way of promotion of TBP from IFF sea bass through the n-3 PUFA recovery by extraction.

Fish farmingSettore BIO/05 - ZoologiaPlant ScienceBiologyBiochemistryEuropean sea baSettore BIO/10 - Biochimicaby-productGeneticsPotential sourceDicentrarchus labraxFood scienceSea bassSettore BIO/06 - Anatomia Comparata E CitologiaMolecular BiologyEcology Evolution Behavior and SystematicsN 3 pufachemistry.chemical_classificationfood and beveragesCell BiologySettore AGR/15 - Scienze E Tecnologie Alimentaribiology.organism_classificationFisherychemistryn-3 polyunsaturated fatty acidLipid contentlipids (amino acids peptides and proteins)Animal Science and ZoologyDicentrarchussense organsFatty acid compositionPUFAPolyunsaturated fatty acid
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Extraction of bioactive compounds from shrimp waste for nutraceutical application

2015

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Settore AGR/20 - ZoocoltureBioactive compoundshrimpe wasteSettore BIO/06 - Anatomia Comparata E Citologianutraceutics
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