6533b85efe1ef96bd12bf3ee
RESEARCH PRODUCT
Species-Specific Antioxidant Power and Bioactive Properties of the Extracts Obtained from Wild Mediterranean Calendula Spp. (Asteraceae)
Theodora IoannouSimona ManuguerraConcetta Maria MessinaAndrea SantulliAngelo TroiaRosaria ArenaGiuseppe RendaEleonora CurcuraciClaire Helliosubject
antioxidantAntioxidantDPPHmedicine.medical_treatmentcalendula specielcsh:Technology01 natural scienceslcsh:Chemistrystresschemistry.chemical_compoundSettore BIO/10 - BiochimicaGeneral Materials ScienceFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaCalendulalcsh:QH301-705.5InstrumentationFluid Flow and Transfer Processes0303 health sciencesbiologyplantsGeneral EngineeringSupercritical fluid extractionlcsh:QC1-999Computer Science ApplicationsSolventantioxidantscalendula speciesopuntia-ficus-indica03 medical and health sciencesmedicineAcetoneby-productspolyphenols030304 developmental biologylcsh:TACLProcess Chemistry and TechnologyExtraction (chemistry)assaybiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistrylcsh:Biology (General)lcsh:QD1-999chemistrylcsh:TA1-2040PolyphenolbioactivitySettore BIO/03 - Botanica Ambientale E Applicataflavonoidsmarigoldsupercritical fluid extraction[SDE.BE]Environmental Sciences/Biodiversity and Ecologylcsh:Engineering (General). Civil engineering (General)lcsh:Physicsphenolic compositiondescription
In this study we focused on four taxa of the genus Calendula (C. maritima, C. suffruticosa subsp. fulgida, C. arvensis, and the hybrid between the first two ones), collected in Mediterranean area (Sicily). Six extracts for each species were obtained using solvents with increasing polarity (hexane, ethanol 80%, acetone 70%, and water) and through extraction by supercritical fluids (SFE). It has been observed that the solvent with the highest extraction efficiency was ethanol 80% for all species. However, SFE extracts showed high antioxidant activity comparable to the ethanol 80% extract (polyphenol, DPPH, and reducing power method). These findings were confirmed by in vitro analysis (MTT assay) where it was observed that the tested concentration (24 µ
year | journal | country | edition | language |
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2019-10-31 | Applied Sciences |