0000000000368120
AUTHOR
Ulrich Peitz
Gastric cancer in autoimmune gastritis: A case-control study from the German centers of the staR project on gastric cancer research
Objectives Patients with autoimmune gastritis (AIG) are reported to have an increased risk of developing gastric cancer (GC). In this study, we assess the characteristics and outcomes of GC patients with AIG in a multicenter case-control study. Methods Between April 2013 and May 2017, patients with GC, including cancers of the esophagogastric junction (EGJ) Siewert type II and III, were recruited. Patients with histological characteristics of AIG were identified and matched in a 1:2 fashion for age and gender to GC patients with no AIG. Presenting symptoms were documented using a self-administered questionnaire. Results Histological assessment of gastric mucosa was available for 572/759 GC …
Different Prevalence of Alarm, Dyspeptic and Reflux Symptoms in Patients with Cardia and Non-cardia Gastric Cancer.
Background and Aims: Symptoms of patients with gastric cancer (GC) are often unspecific and differences in symptoms between patients with cardia and non-cardia GC have been poorly investigated. We aimed to characterize symptoms of patients with cardia and non-cardia GC.
 Methods: Patients with cardia (Siewert type II and III) and non-cardia GC were recruited in the German multicenter cohort of the Gastric Cancer Research (staR) study between 2013 and 2017. Alarm, dyspeptic and reflux symptoms at the time of presentation were documented using a self-administered questionnaire.
 Results: A completed self-administered questionnaire was available for 568/759 recruited patients (132 ca…
Diagnostic Accuracy of <sup>13</sup>C-Urea Breath Test in the Diagnosis of <i>Helicobacter pylori</i> Infection in Patients with Partial Gastric Resection due to Peptic Ulcer Disease
<i>Aims:</i> We investigated the diagnostic properties of the <sup>13</sup>C-urea breath test (<sup>13</sup>C-UBT) prospectively. These are well validated in nonresected patients before and after treatment of <i>Helicobacter pylori</i> infection but not in patients with partial gastric resection due to peptic ulcer disease. <i>Methods:</i> Hospitalized patients with previous gastric resection and indications for upper gastrointestinal endoscopy were recruited for the study. Biopsy specimens were obtained from the fundus mucosa and the gastric remnant adjacent to the gastroenteric anastomosis for histological examination and rapid u…