Real-time PCR for early diagnosis of Rickettsia conorii and prompt management in patients with septic shock and multiple organ failure: two case reports

We herein describe two severe cases of Mediterranean spotted fever caused by Rickettsia conorii. The ar- ticle presents polymerase chain reaction-restriction analysis as an early diagnostic tool for rickettsiosis caused by spotted fever group Rickettsiae. Timely microbiological diagnosis, the combined use of antibi- otics, intensive care measures and a multidisciplinary team approach are fundamental to manage these serious diseases.

Measurement of Ab_FB using inclusive b-hadron decays

Based on a sample of four million events collected by ALEPH from 1991 to 1995, a measurement of the forward-backward asymmetry in Z -> b-barb decays using inclusive final states is presented. High-performance tagging of b-barb events in a wide angular range is achieved using neural network techniques. An optimal hemisphere charge estimator is built by merging primary and secondary vertex information, leading kaon identification and jet charge in a neural network. The average charge asymmetry, the flavour tagging efficiencies and mean b-hemisphere charges are measured from data and used to extract the pole b asymmetry in the Standard Model A^{0,b}_{FB} = 0.1009 +- 0.0027 (stat) +- 0.0015 …

The epidemiology of mumps in Italy.

In Italy, although vaccination has been recommended for a number of years, vaccination coverage for mumps is still sub-optimal. The objective of the present study was to evaluate the seroprevalence of mumps antibodies in the Italian population, stratified by age, gender and geographical area. The proportion of individuals positive for mumps antibodies remained stable in the age classes 0–11 months and 1 year (25.4% and 30.8%, respectively) and showed a continuous increase after the second year of life. The percentage of susceptible individuals was higher than 20% in persons 2–14 years of age and exceeded 10% in persons 15–39 years of age. No statistically significant differences were observ…

Search for scalar leptons in e+e- collisions at centre-of-mass energies up to 209 GeV

A search for selectron, smuon and stau pair production is performed with the data collected by the ALEPH detector at LEP at centre-of-mass energies up to 209 GeV. The numbers of candidate events are consistent with the background predicted by the Standard Model. Final mass limits from ALEPH are reported.

Test of Colour Reconnection Models using Three-Jet Events in Hadronic Z Decays

Hadronic Z decays into three jets are used to test QCD models of colour reconnection (CR). A sensitive quantity is the rate of gluon jets with a gap in the particle rapidity distribution and zero jet charge. Gluon jets are identified by either energy-ordering or by tagging two b-jets. The rates predicted by two string-based tunable CR models, one implemented in JETSET (the GAL model), the other in ARIADNE, are too high and disfavoured by the data, whereas the rates from the corresponding non-CR standard versions of these generators are too low. The data can be described by the GAL model assuming a small value for the R_0 parameter in the range 0.01-0.02.

La produzione biologica in Italia: un'analisi di scenario ed aspetti legislativi

Gli AA. effettuano un’analisi dello scenario relativo alla produzione bio a livello mondiale, europeo e nazionale. In particolare indagano se in Italia l’evoluzione del numero degli operatori del settore risulta in linea con la ritrovata richiesta dei consumatori di poter disporre di un numero crescente di detti prodotti. Tale analisi è stata ulteriormente approfondita al fine di cogliere le eventuali diversità di diffusione del biologico sul territorio italiano, distinto nelle tre macro-aree geografiche Nord, Centro e Sud negli 2000-2007. Per analizzare tali fenomeni sono stati presi in esame le serie storiche dei dati ufficiali disponibili, aggiornati al 2008, provenienti dal Ministero de…

PCSK9-D374Y mediated LDL-R degradation can be functionally inhibited by EGF-A and truncated EGF-A peptides. An in vitro study

Correction to: Major adverse cardiovascular events in non-valvular atrial fibrillation with chronic obstructive pulmonary disease: the ARAPACIS study.

Correction to: Internal and Emergency Medicine (2018) 13:651–660 https://doi.org/10.1007/s11739-018-1835-9 In the original publication, one of the ARAPACIS collaborators Dr. “Leonardo Di Gennaro” name has been erroneously mentioned as “Leonardo De Gennaro”.

Measurement of the W boson Mass and Width in $e^{+}e^{-}$ Collisions at LEP

The mass of the W boson is determined from the direct reconstruction of W decays in WW→qq̄qq̄ and WW→ℓνqq̄ events in e+e- collisions at LEP. The data sample corresponds to an integrated luminosity of 683 pb-1 collected with the ALEPH detector at centre-of-mass energies up to 209 GeV. To minimise any effect from colour reconnection a new procedure is adopted in which low energy particles are not considered in the mass determination from the qq̄qq̄ channel. The combined result from all channels is mW=80.440±0.043(stat.)±0.024(syst.)±0.009(FSI)±0.009(LEP)GeV/c2,where FSI represents the possible effects of final state interactions in the qq̄qq̄ channel and LEP indicates the uncertainty in the b…

European Sero-Epidemiology Network: standardisation of the assay results for pertussis

A standardisation process was developed in order to compare and harmonize serological results of pertussis toxin (PT) antibody measurements performed by laboratories using different technical procedures for detection. This involved the development of a common panel, of sera by a designed reference centre, the distribution of the panel to each participating laboratory for testing with their routine methods, the comparison of the obtained results to those of the reference centre, and the calculation of standardisation equations by regressing the quantitative results against those of the reference centre. As a cut-off indicative of protection against pertussis has not yet been defined, a parti…

Absolute mass lower limit for the lightest neutralino of the MSSM from $e^{+}e^{-}$ data at $\sqrt{s}$ up to 209 GeV

Charginos and neutralinos are searched for in the data collected by the ALEPH experiment at LEP for centre-of-mass energies up to 209 GeV. The negative result of these searches is combined with those from searches for sleptons and Higgs bosons to derive an absolute lower limit of 43.1 GeV/c(2) on the mass of the lightest supersymmetric particle (LSP), assumed to be the,lightest neutralino. This limit is obtained in the framework of the MSSM with R-parity conservation and with gaugino and sfermion mass unification at the GUT scale and assuming no mixing in the stau sector. The LSP limit degrades only slightly to 42.4 GeV/c(2) if stau mixing is considered. Within the more constrained framewor…