Author: Virginia Vandelinder

0000000000368375

AUTHOR

Virginia Vandelinder

showing 1 related works from this author

The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

2019

Nuclear pore complexes form a permeability barrier in vivo that regulates nucleocytoplasmic transport. Here, the authors present a microfluidic device that couples rapid liquid–liquid phase separation of nucleoporins with direct optical interrogation. Freshly formed liquid nucleoporin droplets mimic permeability barrier properties of NPCs.

MicrofluidicsActive Transport Cell Nucleus48BiologyPermeability2303 medical and health sciences0302 clinical medicineReportmedicineMoleculeNuclear poreResearch Articles030304 developmental biology0303 health sciences36Cell Biology34Nuclear Pore Complex ProteinsCell nucleusmedicine.anatomical_structurePermeability (electromagnetism)Nucleocytoplasmic TransportBiophysicsNuclear PoreNucleoporinNuclear transport030217 neurology & neurosurgeryThe Journal of Cell Biology

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