0000000000369150

AUTHOR

Yujie Wang

showing 4 related works from this author

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.

2019

Key Points Question Is birth weight associated with type 2 diabetes and glycemic traits? Findings This mendelian randomization study found that a 1-SD decrease in birth weight due to the genetic risk score was associated with a higher risk of type 2 diabetes among European and East Asian populations. In addition, a 1-SD decrease in birth weight was associated with a 0.189-SD increase in fasting glucose concentration, but not with fasting insulin, 2-hour glucose, or hemoglobin A1c level. Meaning A genetic predisposition to lower birth weight was associated with an increased risk of type 2 diabetes and increased fasting glucose, suggesting potential mechanisms through which perturbation of th…

Blood GlucoseMaleType 2 diabetes0302 clinical medicineOdds RatioBirth WeightInsulin030212 general & internal medicineOriginal Investigation0303 health sciencesAsia EasternMendelian Randomization AnalysisGeneral MedicineMiddle Aged16. Peace & justice3. Good healthOnline OnlyDiabetes and EndocrinologyFemaletype 2 diabetesAdultmedicine.medical_specialtyDiabetes riskAdolescentBirth weightPolymorphism Single NucleotideWhite People03 medical and health sciencesYoung AdultSDG 3 - Good Health and Well-beingAsian PeopleDiabetes mellitusInternal medicineMendelian randomizationmedicineHumans030304 developmental biologyGlycemicAgedGlycated Hemoglobinbusiness.industryResearchInfant Newbornbirth weightGenetic VariationOdds ratioMendelian Randomization Analysismedicine.diseaseDiabetes Mellitus Type 2mendelian randomization studybusinessJAMA network open
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Disentangling boson peaks and Van Hove singularities in a model glass

2018

Using the example of a two-dimensional macroscopic model glass in which the interparticle forces can be precisely measured, we obtain strong hints for resolving a controversy concerning the origin of the anomalous enhancement of the vibrational spectrum in glasses (boson peak). Whereas many authors attribute this anomaly to the structural disorder, some other authors claim that the short-range order, leading to washed-out Van Hove singularities, would cause the boson-peak anomaly. As in our model system, the disorder-induced and shortrange--order-induced features can be completely separated, we are able to discuss the controversy about the boson peak in real glasses in a new light. Our find…

PhysicsMacroscopic modelFOS: Physical sciencesModel system02 engineering and technologyCondensed Matter - Soft Condensed MatterVibrational spectrum021001 nanoscience & nanotechnology01 natural sciencesCoincidenceInterpretation (model theory)Theoretical physics0103 physical sciencesSoft Condensed Matter (cond-mat.soft)Gravitational singularityAnomaly (physics)010306 general physics0210 nano-technologyBoson
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Disorder-induced vibrational anomalies from crystalline to amorphous solids

2021

The origin of boson peak -- an excess of density of states over Debye's model in glassy solids -- is still under intense debate, among which some theories and experiments suggest that boson peak is related to van-Hove singularity. Here we show that boson peak and van-Hove singularity are well separated identities, by measuring the vibrational density of states of a two-dimensional granular system, where packings are tuned gradually from a crystalline, to polycrystals, and to an amorphous material. We observe a coexistence of well separated boson peak and van-Hove singularities in polycrystals, in which the van-Hove singularities gradually shift to higher frequency values while broadening th…

Materials scienceCondensed matter physicsHigh Energy Physics::PhenomenologyVan Hove singularityFOS: Physical sciencesPhysics::OpticsCondensed Matter - Soft Condensed MatterMeasure (mathematics)Amorphous solidCondensed Matter::Soft Condensed MatterVibrational density of statesCondensed Matter::SuperconductivitySoft Condensed Matter (cond-mat.soft)Boson peakPhysical Review Research
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Level statistics and Anderson delocalization in two-dimensional granular materials

2020

Contrary to the theoretical predictions that all waves in two-dimensional disordered materials are localized, Anderson localization is observed only for sufficiently high frequencies in an isotropically jammed two-dimensional disordered granular packing of photoelastic disks. More specifically, we have performed an experiment in analyzing the level statistics of normal mode vibrations. We observe delocalized modes in the low-frequency boson-peak regime and localized modes in the high frequency regime with the crossover frequency just below the Debye frequency. We find that the level-distance distribution obeys Gaussian-Orthogonal-Ensemble (GOE) statistics, i.e. Wigner-Dyson distribution, in…

PhysicsAnderson localizationFOS: Physical sciences02 engineering and technologyCondensed Matter - Soft Condensed Matter021001 nanoscience & nanotechnologyGranular material01 natural sciencesDebye frequencyDelocalized electronNormal mode0103 physical sciencesStatisticsExponentSoft Condensed Matter (cond-mat.soft)010306 general physics0210 nano-technologyScalingAnderson impurity model
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