PROCESSI DI DOMESTICAZIONE: UN CONTRIBUTO DALLE ANALISI DEL DNA MITOCONDRIALE DI ANTICHI REPERTI SCHELETRICI BOVINI (BOS PRIMIGENIUS 19.000 BP)

The origin of european cattle: Evidence from modern and ancient DNA.

The origin of European cattle: evidence from modern and ancient DNA. Beja-Pereira A, Caramelli D, Lalueza-Fox C, Vernesi C, Ferrand N, Casoli A, Goyache F, Royo LJ, Conti S, Lari M, Martini A, Ouragh L, Magid A, Atash A, Zsolnai A, Boscato P, Triantaphylidis C, Ploumi K, Sineo L, Mallegni F, Taberlet P, Erhardt G, Sampietro L, Bertranpetit J, Barbujani G, Luikart G, Bertorelle G. Source Centro de Investigação em Biodiversidade e Recursos Genéticos (CIBIO-UP) and Secção Autónoma de Engenharia de Ciências Agrárias, Universidade do Porto, 4485-661 Vairão, Portugal. Abstract Cattle domestication from wild aurochsen was among the most important innovations during the Neolithic agricultural revol…

Perspective validation of the eurofever classification criteria for monogenic periodic fevers.

We recently proposed a set of provisional, evidence-based, clinical criteria for the classification of children and adults patients affected by monogenic periodic fevers. These criteria, built and validated in a cohort of 1215 patients with periodic fever enrolled in the Eurofever Registry from November 2009 to February 2013, displayed a high sensitivity and specificity.

Albumin replacement in patients with severe sepsis or septic shock.

BACKGROUND: Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum albumin concentration was 30 g per liter or more until discharge from the ICU or 28 days after randomization. The primary outcome was death from any cause at 28 days. Secondary outcomes were death from any cause at 90 days, the number of patients with or…