0000000000370123
AUTHOR
L. Martínez
Bladder cancer index : Cross-cultural adaptation into Spanish and psychometric evaluation
Background: The Bladder Cancer Index (BCI) is so far the only instrument applicable across all bladder cancer patients, independent of tumor infiltration or treatment applied. We developed a Spanish version of the BCI, and assessed its acceptability and metric properties. Methods: For the adaptation into Spanish we used the forward and back-translation method, expert panels, and cognitive debriefing patient interviews. For the assessment of metric properties we used data from 197 bladder cancer patients from a multi-center prospective study. The Spanish BCI and the SF-36 Health Survey were self-administered before and 12 months after treatment. Reliability was estimated by Cronbach's alpha.…
Low Energy Gamma Ray Imager (LEGRI)
The Low Energy Gamma Ray Imager (LEGRI) will be one of the three instruments carried by the first MINISAT mission. LEGRI aims to demonstrate the technological feasibility of a new generation of low energy gamma-ray telescopes with imaging, medium resolution spectroscopy and high continuum sensitivity in the 20-200 keV spectral region, based on HgI2 solid state detector technology.
La Cueva de El Sidrón (Piloña Asturias)
Estado de las excavaciones y estudios en la Cueva de El Sidrón (PIloña, Asturias).
Towards light-mediated sensing of bacterial comfort
Abstract Bacterial comfort is central to biotechnological applications. Here, we report the characterization of different sensoring systems, the first step within a broader synthetic biology-inspired light-mediated strategy to determine Escherichia coli perception of environmental factors critical to bacterial performance. We did so by directly ‘asking’ bacterial cultures with light-encoded questions corresponding to the excitation wavelength of fluorescent proteins placed under the control of environment-sensitive promoters. We built four genetic constructions with fluorescent proteins responding to glucose, temperature, oxygen and nitrogen; and a fifth construction allowing UV-induced exp…