0000000000372763

AUTHOR

Massimo Cavallaro

Additional file 2 of 3 ′-5 ′ crosstalk contributes to transcriptional bursting

Additional file 2 Review history.

research product

Three-dimensional transesophageal echocardiography in the guide of cardiac mass biopsy

Cardiac tumors are rare. Cardiovascular imaging is more important in the differential diagnosis of cardiac masses but no current noninvasive diagnostic tool has the ability to absolutely diagnose cardiac tumors. In effect cardiac biopsy remains the gold standard in the differential diagnosis. In our case we show the advantages of three-dimensional (3D) transesophageal echocardiography as a guide for cardiac biopsy. We believe that 3D TEE is ready to be used in the guide of cardiac mass biopsy. Once interventionalists become confident with 3D imaging, this technique should be used routinely during these procedures.

research product

3 ′-5 ′ crosstalk contributes to transcriptional bursting

Abstract Background Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contributing to transcriptional bursting have been identified, usually classified as intrinsic, in other words local to single genes, or extrinsic, relating to the macroscopic state of the cell. However, some possible contributors have not been explored yet. Here, we focus on processes at the 3 ′ and 5 ′ ends of a gene that enable reinitiation of transcription upon termination. Results Using Bay…

research product

Additional file 1 of 3 ′-5 ′ crosstalk contributes to transcriptional bursting

Additional file 1 “Supporting Information to: “3’-5’ crosstalk contributes to transcriptional bursting”.

research product

Supporting data to M. Cavallaro, et al., 3'-5' crosstalk contributes to transcriptional bursting, 2019

This repository contains supporting data to reference [1]. Please cite [1] if you find this repository useful. The data include: Flow cytometry data of HBB and HIV transgenes' expression in `.fcs` format. NanoString data for HIV expression. smFISH data for HBB and Akt1 gene expression. [1] M. Cavallaro, et al., 3'-5' interactions contribute to transcriptional bursting, bioR$\chi$iv 514174. https://doi.org/10.1101/514174

research product

mcavallaro/gLoop: Supporting software to M. Cavallaro, et al., 3'-5' crosstalk contributes to transcriptional bursting, 2020

This repository contains supporting software to reference [1]. Please cite [1] if you find this repository useful. [1] M. Cavallaro, et al., 3'-5' interactions contribute to transcriptional bursting, bioR$\chi$iv 514174. https://doi.org/10.1101/5141

research product