0000000000373080

AUTHOR

B. Kosaras

showing 3 related works from this author

Depressive effect of LHRH on the numbers of "synaptic" ribbons and spherules in the pineal gland of diestrous rats.

1983

Previous studies have shown that LHRH or LHRH-like substances are present in the pineal gland. In order to investigate whether exogenous LHRH may affect the pineal gland, in the present study the effects of a single dose of LHRH (1 microgram, i.p.) on pineal "synaptic" ribbons and spherules as well as serum melatonin levels were examined in diestrous Wistar rats. One hour after the injection both ribbons and spherules exhibited a statistically significant decrease in number. Serum melatonin levels were not affected. It is concluded that humoral feedback mechanisms may exist between the hypothalamus and the pineal gland.

endocrine systemmedicine.medical_specialtyHistologyBiologyPineal GlandPathology and Forensic MedicineMelatoninGonadotropin-Releasing HormonePineal glandPregnancyInternal medicinemedicineAnimalsMelatoninRats Inbred StrainsCell BiologyDiestrusRatsEndocrinologymedicine.anatomical_structurenervous systemHypothalamusSynapsesFemalesense organshormones hormone substitutes and hormone antagonistsmedicine.drugCell and tissue research
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Pineal ?synaptic? ribbons and spherules during the estrous cycle in rats

1983

In previous studies pineal "synaptic" ribbons have been shown to undergo striking numerical changes under various physiological and experimental conditions and to be regulated by beta-adrenergic mechanisms. The aim of the present investigation was to study the numbers of pineal "synaptic" ribbons and spherules in Wistar rats throughout the estrous cycle and to compare them with those in males. There were no statistically significant differences in the numbers of ribbons and spherules between males and females and in the females at the different stages of the estrous cycle, indicating that the structures in question, in vivo, do not appear to be regulated by naturally occurring changes of se…

Maleendocrine systemEmbryologymedicine.medical_specialtyBiologyPineal GlandPineal glandSex FactorsEstrusPregnancySex factorsIn vivoInternal medicinemedicineAnimalsEstrous cycleSex Steroid HormonesRats Inbred StrainsCell BiologyRatsMicroscopy Electronmedicine.anatomical_structureEndocrinologynervous systemSynapsesFemalesense organsAnatomyhormones hormone substitutes and hormone antagonistsDevelopmental BiologyAnatomy and Embryology
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Influence of melatonin and serotonin on the number of rat pineal ?synaptic? ribbons and spherules in vitro

1985

Previous studies have shown that the "synaptic" ribbons (SR) and spherules (SS) of the mammalian pineal gland may respond differently under physiological and various experimental conditions. The aim of the present study was to gain insight into the mechanisms that may be responsible for the numerical changes of these organelles during a 24-h cycle. As the possibility exists that the structures are influenced by substances synthesized within the pinealocyte, rat pineal glands were cultured with and without added melatonin or serotonin, using an experimental protocol such that the addition of melatonin and serotonin mimicks the circadian changes of the respective substances within the pineal.…

MaleSerotoninendocrine systemmedicine.medical_specialtyHistologyBiologyOrgan culturePineal GlandPathology and Forensic MedicinePinealocyteMelatoninPineal glandInternal medicineOrganellemedicineAnimalsCircadian rhythmIncubationCells CulturedMelatoninRats Inbred StrainsCell BiologyRatsOrganoidsmedicine.anatomical_structureEndocrinologySynapsesSerotoninhormones hormone substitutes and hormone antagonistsmedicine.drugCell and Tissue Research
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