0000000000374687

AUTHOR

Alexander Sterlin

showing 4 related works from this author

An experimental study on long term outcomes after magnetic esophageal compression anastomosis in piglets

2021

Abstract Background/Purpose Previous studies have shown that a patent, watertight esophageal anastomosis can be accomplished safely using specially-shaped magnets in piglets. However, it is unclear whether such a magnetic esophageal compression anastomosis (MECA) remains patent in the long-term. The purpose of this study was to evaluate the long-term outcome of MECA in an experimental pig model over an observation period of 2 months. Methods Ten piglets underwent creation of an MECA with custom-made 8 mm magnets and a U-shaped esophageal bypass loop to allow peroral nutrition at eight weeks of life. Two weeks later, the bypass loop was closed surgically, requiring the pigs to swallow via th…

medicine.medical_specialtyEndoscopeSwineAnastomosisMagneticsmedicineAnimalsEsophagusEsophageal Atresiabusiness.industryMagnetic PhenomenaAnastomosis SurgicalGeneral Medicinemedicine.diseaseDysphagiaConfidence intervalSurgerymedicine.anatomical_structureAtresiaPediatrics Perinatology and Child HealthMagnetsSurgeryHistopathologymedicine.symptombusinessWeight gainJournal of Pediatric Surgery
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Novel Device for Endoluminal Esophageal Atresia Repair: First-in-Human Experience

2021

Thoracoscopic esophageal atresia (EA) repair affords many benefits to the patient; however, intracorporeal suturing of the anastomosis is technically challenging. Esophageal magnetic compression anastomosis (EMCA) is a compelling option for endoluminal EA repair, but available EMCA devices have prohibitive rates of recalcitrant stricture. Connect-EA is a new endoluminal EMCA device system that employs 2 magnetic anchors with a unique mating geometry designed to reliably create a robust anastomosis and decrease rates of leak and stricture. We describe our first-in-human experience with this novel endoluminal device for staged EA repair in 3 patients (Gross type A, B, and C) at high risk for …

medicine.medical_specialtyLeakAnastomotic LeakGestational AgeAnastomosismedicineHumansEsophageal AtresiaSurgical repairmedicine.diagnostic_testbusiness.industryThoracoscopyAnastomosis SurgicalInfant NewbornEquipment DesignPerioperativeFirst in humanEsophageal anastomosismedicine.diseaseDilatationSurgeryEndoscopyTreatment OutcomeAtresiaPediatrics Perinatology and Child HealthEsophageal StenosisMagnetsEsophagoscopybusinessInfant PrematurePediatrics
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An experimental study on magnetic esophageal compression anastomosis in piglets.

2019

Abstract Introduction Fashioning a patent, watertight anastomosis in patients with esophageal atresia is a challenging task in pediatric surgery, particularly when performed under tension. A reproducible suture-less alternative would decrease operative time. We evaluated magnetic esophageal compression anastomoses in a novel bypass-loop swine model. Methods Eight-week-old piglets underwent thoracotomy to mobilize the esophagus at the carina to create a U-shaped loop. Custom-made 8 mm diameter Neodymium Magnets were inserted into the esophagus proximal and distal to the loop, then mated side-to-side at the future anastomosis site. Pigs were observed for 8 (n = 4), 10 (n = 6), and 12 (n = 2) …

medicine.medical_specialtyLeakSwinemedicine.medical_treatmentRadiographyAnastomosis03 medical and health sciences0302 clinical medicineEsophagusPregnancy030225 pediatricsPediatric surgerymedicineAnimalsThoracotomyEsophagusEsophageal Atresiabusiness.industryAnastomosis SurgicalGeneral Medicinemedicine.diseaseSurgeryDisease Models Animalmedicine.anatomical_structure030220 oncology & carcinogenesisAtresiaPediatrics Perinatology and Child HealthMagnetsSurgeryHistopathologyFemalebusinessJournal of pediatric surgery
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Extrathoracic Lengthening (Kimura Technique)

2021

Treatment of congenital long gap esophageal atresia is extremely challenging. Cases are rare, variable, and oftentimes complex. Possible treatment options include delayed primary repair after initial gastrostomy, gastric transposition, intestinal interpositions, traction procedures, myotomy, and gastric tube techniques. Treatment strategies often consist of variations and combinations of different approaches.

Myotomymedicine.medical_specialtyLong gapbusiness.industrymedicine.medical_treatmentTreatment optionsLong gap esophageal atresiaGastrostomySurgeryPrimary repairMedicineTreatment strategyGastric transpositionbusiness
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