Differentiation between Brain Metastasis and Glioblastoma using MRI and two-dimensional Turbo Spectroscopic Imaging data

In this paper we propose a novel technique to differentiate brain metastases from high-grade gliomas, which represent the most aggressive and common brain lesions. In spite of the significant progresses achieved in the field of MRI in the last decades, the differentiation between these two types of tumors is still a challenge as they show a similar appearance on MRI images, but require a completely different therapeutic treatment. Here, we show that such a differentiation is actually possible and can be obtained by making use of MRI as well as of two-dimensional Turbo Spectroscopic Imaging (2D-TSI) information. Specifically, the proposed technique consists of three steps: we first detect th…