Regulation of Macromolecular Synthesis during Sea Urchin Development

Immediately following fertilization the sea urchin egg enters a period of very rapid cell division that cleaves the egg cell into about one thousand proportionately smaller cells, which form the swimming blastula, i.e. a larval form that is less vulnerable to environmental injuries since it is capable of actively swimming away from them.

The role of cell interactions in the control of RNA synthesis.

Antigen-distribution in rat liver mitochondria.

I mitocondri di fegato di ratto possiedono almeno tre gruppi di antigeni, dei quali uno e esclusivamente legato alle membrane mitocondriali, uno e presente nella frazione solubile in 0,3% desossicolato di sodio ed un altro, che, sebbene principalmente localizzato nelle membrane, e anche dimostrabile nella frazione desossicolato solubile.

Synthesis of RNA in isolated nuclei of sea urchin embryos.

It is demonstrated that isolated nuclei of sea urchin embryos are able to incorporate radioactive nucleotides into RNA. Some properties of the incorporation system are described.

[The activation of methionine for transmethylation in regenerating rat liver and hepatoma].

The activity of methionine-activating enzyme has been measured in normal and regenerating rat liver and in hepatoma cells.

Immunological and electrophoretic analysis of rat liver mitochondria and other cellular fractions*1

Abstract The combination of electrophoretic and immunological analysis has demonstrated a powerful method for the study of subcellular components. Rat liver mitochondria seem to be composed of at least 12 components, either anodic or cathodic. Detergents have been used to dissolve mitochondria. The electrophoretic behaviour of complexes among such agents and mitochondria proteins is described. The treatment of mitochondria with deoxycholate between 0.1-0.5 per cent final concentration showed that some antigens are progressively brought into solution by such treatment, while others are firmly bound to the mitochondrial membranes. Among the other subcellular fractions, the microsomes exhibit …