0000000000377082

AUTHOR

M.f. Neurath

showing 3 related works from this author

Structure and Function of Matrix Components in the Cruciate Ligaments

1992

In the present study, the matrix components of 100 cruciate ligaments were analyzed by conventional electron microscopy, immunohistology, morphometry, and immunoelectron microscopy. The anterior (ACL) and the posterior (PCL) cruciate ligaments contained collagen types III, IV, and VI. Several structural glycoproteins, like fibronectin, laminin, entactin, tenascin, and undulin were detected using monoclonal antibodies. Whereas laminin and entactin were higher concentrated in the PCL, type VI collagen was more frequently found in the ACL. The ACL had a critical nourishment in its distal and middle thirds. In all ligament parts the PCL revealed a better vascular supply with strong correlation …

Pathologymedicine.medical_specialtyHistologybiologyChemistryImmunoelectron microscopyTenascinmusculoskeletal systemExtracellular matrixFibronectinCruciate ligamentType IV collagenmedicine.anatomical_structureLamininbiology.proteinmedicineLigamentAnatomyhuman activitiesCells Tissues Organs
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Imaging techniques in inflammatory bowel disease: recent trends, questions and answers

2009

Summary Imaging techniques have undergone substantial progress in recent years and contribute significantly in the diagnosis of inflammatory bowel diseases in conjunction with patient history, clinical and laboratory examination. Modern cross-sectional imaging modalities such as computed tomography and magnetic resonance imaging allow an evaluation not only of the complete bowel wall of the small intestine, but also of extraluminal structures. They constitute a major diagnostic component in the initial workup, in stricturing or fistulizing disease and in suspected abscess. Transabdominal ultrasonography has been re-appreciated in these settings as an easy- and ready-to-use tool yielding rea…

Diagnostic Imagingmedicine.medical_specialtyContrast MediaColonoscopySensitivity and SpecificityInflammatory bowel diseaseChromoendoscopyDiagnosis DifferentialCrohn DiseasePredictive Value of TestsmedicineEndomicroscopyHumansMedical historyClinical Trials as TopicMicroscopy Confocalmedicine.diagnostic_testbusiness.industryGastroenterologyMagnetic resonance imagingColonoscopyGeneral MedicineInflammatory Bowel Diseasesmedicine.diseaseMagnetic Resonance ImagingUlcerative colitisPositron emission tomographyPositron-Emission TomographyColitis UlcerativeRadiologyTomography X-Ray ComputedbusinessGastroentérologie Clinique et Biologique
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Dynamic in vivo Imaging of Microvasculature and Perfusion by Miniaturized Confocal Laser Microscopy

2008

<i>Introduction:</i> Microvasculature and associated pathologies mandate dynamic imaging. We evaluated a novel miniaturized confocal laser scanning probe for in vivo visualization of blood vessels, blood flow, cell tracking and perfusion in both healthy rodents and disease models.<i> Methods:</i> The hand-held confocal microscopy system allowed a 500- to 2,400-fold magnification at a dynamically variable imaging depth. Different intravital stains were used alone or in combination for tissue, nuclear, plasma and vascular endothelial cell staining and for blood flow visualization, and targeted staining for individual cell populations. <i>Results:</i> Precis…

MaleMice Inbred MRL lprPathologymedicine.medical_specialtyMaterials scienceLaser scanningDynamic imagingConfocalCell Communicationlaw.inventionMiceImaging Three-DimensionalIn vivoConfocal microscopylawMicroscopyLeukocytesmedicineAnimalsFluorescent DyesInflammationMicroscopy ConfocalMiniaturizationMicrocirculationBrainEndothelial CellsThrombosisLupus NephritisMice Inbred C57BLDisease Models AnimalMicrovesselsFemaleSurgeryIntracranial ThrombosisGerbillinaePerfusionBlood Flow VelocityPreclinical imagingBiomedical engineeringEuropean Surgical Research
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