0000000000379268
AUTHOR
David Smith
Exploring Broadband GRB Behavior During gamma-ray Emission
The robotic ROTSE-III telescope network detected prompt optical emission contemporaneous with the gamma-ray emission of Swift events GRB051109A and GRB051111. Both datasets have continuous coverage at high signal-to-noise levels from the prompt phase onwards, thus the early observations are readily compared to the Swift XRT and BAT high energy detections. In both cases, the optical afterglow is established, declining steadily during the prompt emission. For GRB051111, there is evidence of an excess optical component during the prompt emission. The component is consistent with the flux spectrally extrapolated from the gamma-rays, using the gamma-ray spectral index. A compilation of spectral …
Measurement ofνμandν¯μinduced neutral current singleπ0production cross sections on mineral oil atEν∼O(1 GeV)
MiniBooNE reports the first absolute cross sections for neutral current single {pi}{sup 0} production on CH{sub 2} induced by neutrino and antineutrino interactions measured from the largest sets of NC {pi}{sup 0} events collected to date. The principal result consists of differential cross sections measured as functions of {pi}{sup 0} momentum and {pi}{sup 0} angle averaged over the neutrino flux at MiniBooNE. We find total cross sections of (4.76 {+-} 0.05{sub stat} {+-} 0.40{sub sys}) x 10{sup -40} cm{sup 2}/nucleon at a mean energy of = 808 MeV and (1.48 {+-} 0.05{sub stat} {+-} 0.14{sub sys}) x 10{sup -40} cm{sup 2}/nucleon at a mean energy of = 664 MeV for {nu}{sub {mu}} and {bar {nu}…
Measurement ofνμ-induced charged-current neutral pion production cross sections on mineral oil atEν∈0.5–2.0 GeV
The authors would like to acknowledge the support of Fermilab, the Department of Energy, and the National Science Foundation in the construction, operation, and data analysis of the Mini Booster Neutrino Experiment.
Dual baseline search for muon neutrino disappearance at0.5 eV2<Δm2<40 eV2
The SciBooNE and MiniBooNE collaborations report the results of a νμ disappearance search in the Δ'm2 region of 0.5-40 eV2. The neutrino rate as measured by the SciBooNE tracking detectors is used to constrain the rate at the MiniBooNE Cherenkov detector in the first joint analysis of data from both collaborations. Two separate analyses of the combined data samples set 90% confidence level (CL) limits on νμ disappearance in the 0.5-40 eV2 Δm2 region, with an improvement over previous experimental constraints between 10 and 30 eV2
Test of Lorentz and CPT violation with short baseline neutrino oscillation excesses
The sidereal time dependence of MiniBooNE ν[subscript e] and ν[over-bar][subscript e] appearance data is analyzed to search for evidence of Lorentz and CPT violation. An unbinned Kolmogorov–Smirnov (K–S) test shows both the ν[subscript e] and ν[over-bar][subscript e] appearance data are compatible with the null sidereal variation hypothesis to more than 5%. Using an unbinned likelihood fit with a Lorentz-violating oscillation model derived from the Standard Model Extension (SME) to describe any excess events over background, we find that the ν[subscript e] appearance data prefer a sidereal time-independent solution, and the ν[over-bar][subscript e] appearance data slightly prefer a sidereal…
Measurement of the neutrino neutral-current elastic differential cross section on mineral oil atEν∼1 GeV
We report a measurement of the flux-averaged neutral-current elastic differential cross section for neutrinos scattering on mineral oil (CH{sub 2}) as a function of four-momentum transferred squared, Q{sup 2}. It is obtained by measuring the kinematics of recoiling nucleons with kinetic energy greater than 50 MeV which are readily detected in MiniBooNE. This differential cross-section distribution is fit with fixed nucleon form factors apart from an axial mass M{sub A} that provides a best fit for M{sub A}=1.39{+-}0.11 GeV. Using the data from the charged-current neutrino interaction sample, a ratio of neutral-current to charged-current quasielastic cross sections as a function of Q{sup 2} …
RANDOMIZED PHASE II STUDY OF FIRST-LINE EVEROLIMUS (EVE) + BEVACIZUMAB (BEV) VERSUS INTERFERON ALFA-2A (IFN) + BEV IN PATIENTS (PTS) WITH METASTATIC RENAL CELL CARCINOMA (MRCC): RECORD-2
ABSTRACT Background Study results demonstrated that IFN augments BEV activity and improves median PFS in pts with mRCC. Thus, combination BEV + IFN is a standard first-line treatment option for mRCC. Combining BEV with the mTOR inhibitor EVE may be an efficacious and well-tolerated treatment option. The open-label, phase II RECORD-2 trial compared first-line EVE + BEV and IFN + BEV in mRCC. Patients and methods: Therapy-naive pts with clear cell mRCC and prior nephrectomy were randomized 1:1 to BEV 10 mg/kg IV every 2 weeks with either EVE 10 mg oral daily or IFN (9 MIU SC 3 times/week, if tolerated). Tumour assessments were every 12 weeks. Primary objective was treatment effect on progress…
New ECCO model documents for Material Deposit and Transfer Agreements in compliance with the Nagoya Protocol
The European Culture Collections Organisation presents two new model documents for Material Deposit Agreement (MDA) and Material Transfer Agreement (MTA) designed to enable microbial culture collection leaders to draft appropriate agreement documents for, respectively, deposit and supply of materials from a public collection. These tools provide guidance to collections seeking to draft an MDA and MTA, and are available in open access to be used, modified, and shared. The MDA model consists of a set of core fields typically included in a deposit form to collect relevant information to facilitate assessment of the status of the material under access and benefit sharing (ABS) legislation. It a…
ACTIVATION (PercutAneous Coronary inTervention prIor to transcatheter aortic VAlve implantaTION)
Abstract Objectives This study sought to determine if percutaneous coronary intervention (PCI) prior to transcatheter aortic valve replacement (TAVR) in patients with significant coronary artery disease would produce noninferior clinical results when compared with no PCI (control arm). Background PCI in patients undergoing TAVR is not without risk, and there are no randomized data to inform clinical practice. Methods Patients with severe symptomatic aortic stenosis and significant coronary artery disease with Canadian Cardiovascular Society class ≤2 angina were randomly assigned to receive PCI or no PCI prior to TAVR. The primary endpoint was a composite of all-cause death or rehospitalizat…
Search for Muon Neutrino and Antineutrino Disappearance in MiniBooNE
The MiniBooNE Collaboration reports a search for nu(mu) and nu(mu) disappearance in the Delta m(2) region of 0.5-40 eV(2). These measurements are important for constraining models with extra types of neutrinos, extra dimensions, and CPT violation. Fits to the shape of the nu(mu) and nu(mu) energy spectra reveal no evidence for disappearance at the 90% confidence level (C.L.) in either mode. The test of nu(mu) disappearance probes a region below Delta m(2)=40 eV(2) never explored before.
Neutrino flux prediction at MiniBooNE
The booster neutrino experiment (MiniBooNE) searches for nu(mu)->nu(e) oscillations using the O(1 GeV) neutrino beam produced by the booster synchrotron at the Fermi National Accelerator Laboratory). The booster delivers protons with 8 GeV kinetic energy (8.89 GeV/c momentum) to a beryllium target, producing neutrinos from the decay of secondary particles in the beam line. We describe the Monte Carlo simulation methods used to estimate the flux of neutrinos from the beam line incident on the MiniBooNE detector for both polarities of the focusing horn. The simulation uses the Geant4 framework for propagating particles, accounting for electromagnetic processes and hadronic interactions in the…
Unexplained Excess of Electronlike Events from a 1-GeV Neutrino Beam
The MiniBooNE Collaboration observes unexplained electronlike events in the reconstructed neutrino energy range from 200 to 475 MeV. With 6.46 x 10(20) protons on target, 544 electronlike events are observed in this energy range, compared to an expectation of 415.2 +/- 43.4 events, corresponding to an excess of 128.8 +/- 20.4 +/- 38.3 events. The shape of the excess in several kinematic variables is consistent with being due to either nu(e) and (nu) over bar (e) charged-current scattering or nu(mu) neutral-current scattering with a photon in the final state. No significant excess of events is observed in the reconstructed neutrino energy range from 475 to 1250 MeV, where 408 events are obse…