0000000000379543

AUTHOR

Giuseppe Vona

showing 3 related works from this author

Human Y-chromosome variation in the Western Mediterranean area: Implications for the peopling of the region

2001

Y-chromosome variation was analyzed in a sample of 1127 males from the Western Mediterranean area by surveying 16 biallelic and 4 multiallelic sites. Some populations from Northeastern Europe and the Middle East were also studied for comparison. All Y-chromosome haplotypes were included in a parsimonious genealogic tree consisting of 17 haplogroups, several of which displayed distinct geographic specificities. One of the haplogroups, HG9.2, has some features that are compatible with a spread into Europe from the Near East during the Neolithic period. However, the current distribution of this haplogroup would suggest that the Neolithic gene pool had a major impact in the eastern and central …

MaleImmunologyMediterranean BasinHaplogroupGene flowMiddle Eastwest mediterranean basinAfrica NorthernY ChromosomeGenetic variationHumansImmunology and Allergyy-chromosome polymorphismsAllelesRecombination GeneticGeneticsPolymorphism GeneticMiddle EastMediterranean Regioneuropean populationsy-chromosome haplogroupsHaplotypeGenetic VariationGeneral MedicinehumanitiesEuropeGeographyHaplotypesEvolutionary biologyMultivariate AnalysisPeriod (geology)Gene poolgeographic locationseuropean populations; west mediterranean basin; y-chromosome haplogroups; y-chromosome polymorphismsMicrosatellite Repeats
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Patterns of male-specific inter-population divergence in Europe, West Asia and North Africa

2000

summary We typed 1801 males from 55 locations for the Y-specific binary markers YAP, DYZ3, SRY "!)$" and the (CA)n microsatellites YCAII and DYS413. Phylogenetic relationships of chromosomes with the same binary haplotype were condensed in seven large one-step networks, which accounted for 95% of all chromosomes. Their coalescence ages were estimated based on microsatellite diversity. The three largest and oldest networks undergo sharp frequency changes in three areas. The more recent network 3‐1A clearly discriminates between Western and Eastern European populations. Pairwise Fst showed an overall increment with increasing geographic distance but with a slope greatly reduced when compared …

MalehaplotypePopulation geneticsVariation (Genetics)phylogenyAfrica NorthernModelsY Chromosomegenetic variabilitypopulation dynamicsNorthernDinucleotide RepeatsGenetics (clinical)education.field_of_studyPhylogenetic treeGeographyarticlechromosome analysislinguisticsStatisticalEastern europeanEuropeGeographypriority journalMicrosatelliteWesternmarker geneAsiaEvolutionPopulationPopulationmicrosatellite DNA; article; Asia; chromosome analysis; controlled study; Europe; genetic variability; geographic distribution; haplotype; human; linguistics; male; marker gene; normal human; North Africa; phylogeny; population dynamics; priority journal; Africa Northern; Asia Western; Dinucleotide Repeats; Europe; Evolution Molecular; Genetics Population; Geography; Haplotypes; Humans; Male; Microsatellite Repeats; Models Genetic; Models Statistical; Variation (Genetics); Y ChromosomeY chromosomeEvolution MolecularGeneticGeographical distancegeographic distributionAsia WesternGeneticsHumanscontrolled studyhumannormal humaneducationModels StatisticalModels GeneticHaplotypeGenetic VariationMolecularNorth AfricaSettore BIO/18 - GeneticaGenetics PopulationHaplotypesEvolutionary biologyAfricamicrosatellite DNAMicrosatellite Repeats
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Tracing European Founder Lineages in the Near Eastern mtDNA Pool

2000

Founder analysis is a method for analysis of nonrecombining DNA sequence data, with the aim of identification and dating of migrations into new territory. The method picks out founder sequence types in potential source populations and dates lineage clusters deriving from them in the settlement zone of interest. Here, using mtDNA, we apply the approach to the colonization of Europe, to estimate the proportion of modern lineages whose ancestors arrived during each major phase of settlement. To estimate the Palaeolithic and Neolithic contributions to European mtDNA diversity more accurately than was previously achievable, we have now extended the Near Eastern, European, and northern-Caucasus d…

Time FactorsHaplogroup HLineage (evolution)Extrachromosomal InheritanceBiologyDNA MitochondrialHaplogroupMiddle East03 medical and health sciencesGene FrequencyDemic diffusionGeneticsHumansGenetics(clinical)PhylogenyGenetics (clinical)030304 developmental biologyGenetics0303 health sciences030305 genetics & heredityGenetic VariationGene PoolArticlesHaplogroup L3Emigration and ImmigrationFounder EffectEuropeDatabases as TopicHaplotypesMutagenesisEvolutionary biologyGenealogical DNA testHuman mitochondrial DNA haplogroupFounder effectThe American Journal of Human Genetics
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