6533b7ddfe1ef96bd12748f9
RESEARCH PRODUCT
Patterns of male-specific inter-population divergence in Europe, West Asia and North Africa
V. BakalliEmmanuel I. MichalodimitrakisP SantolamazzaAndrea NovellettoAndrea NovellettoAntonio TorroniAntonio TorroniJadwiga JaruzelskaJüri ParikPatrizia MalaspinaLaurent VaresiRadim BrdickaA. I. KozlovGiuseppe VonaBoris MalyarchukMihaela StefanRichard VillemsSyed Qasim MehdiNejat AkarM. StenicoValentino RomanoL. TerrenatoMarc MemmiFulvio CrucianiRosaria ScozzariA. Pangraziosubject
MalehaplotypePopulation geneticsVariation (Genetics)phylogenyAfrica NorthernModelsY Chromosomegenetic variabilitypopulation dynamicsNorthernDinucleotide RepeatsGenetics (clinical)education.field_of_studyPhylogenetic treeGeographyarticlechromosome analysislinguisticsStatisticalEastern europeanEuropeGeographypriority journalMicrosatelliteWesternmarker geneAsiaEvolutionPopulationPopulationmicrosatellite DNA; article; Asia; chromosome analysis; controlled study; Europe; genetic variability; geographic distribution; haplotype; human; linguistics; male; marker gene; normal human; North Africa; phylogeny; population dynamics; priority journal; Africa Northern; Asia Western; Dinucleotide Repeats; Europe; Evolution Molecular; Genetics Population; Geography; Haplotypes; Humans; Male; Microsatellite Repeats; Models Genetic; Models Statistical; Variation (Genetics); Y ChromosomeY chromosomeEvolution MolecularGeneticGeographical distancegeographic distributionAsia WesternGeneticsHumanscontrolled studyhumannormal humaneducationModels StatisticalModels GeneticHaplotypeGenetic VariationMolecularNorth AfricaSettore BIO/18 - GeneticaGenetics PopulationHaplotypesEvolutionary biologyAfricamicrosatellite DNAMicrosatellite Repeatsdescription
summary We typed 1801 males from 55 locations for the Y-specific binary markers YAP, DYZ3, SRY "!)$" and the (CA)n microsatellites YCAII and DYS413. Phylogenetic relationships of chromosomes with the same binary haplotype were condensed in seven large one-step networks, which accounted for 95% of all chromosomes. Their coalescence ages were estimated based on microsatellite diversity. The three largest and oldest networks undergo sharp frequency changes in three areas. The more recent network 3‐1A clearly discriminates between Western and Eastern European populations. Pairwise Fst showed an overall increment with increasing geographic distance but with a slope greatly reduced when compared to previous reports. By sectioning the entire data set according to geographic and linguistic criteria, we found higher Fst-on-distance slopes within Europe than in West Asia or across the two continents.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-01-01 |