Search results for "Northern"

showing 10 items of 492 documents

Revising midlatitude summer temperatures back to A.D. 600 based on a wood density network

2015

Annually resolved and millennium-long reconstructions of large-scale temperature variability are primarily composed of tree ring width (TRW) chronologies. Changes in ring width, however, have recently been shown to bias the ratio between low- and high-frequency signals. To overcome limitations in capturing the full spectrum of past temperature variability, we present a network of 15 maximum latewood density (MXD) chronologies distributed across the Northern Hemisphere extratropics. Independent subsets of continental-scale records consistently reveal high MXD before 1580 and after 1910, with below average values between these periods. Reconstructed extratropical summer temperatures reflect n…

Northern HemisphereTree ringsClimate changeG Geography (General)Dendroclimatology3rd-DASAtmospheric sciencesAtmosphereMaximum latewood densityVolcanic coolingGeophysicsMillennial reconstructionMiddle latitudesClimatologyPaleoclimatologyG1Extratropical cycloneDendrochronologyLittle Ice AgeGeneral Earth and Planetary SciencesBeta valueGeology
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Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver

1992

AbstractThe process of peroxisome proliferation in rodent liver by hypolipidemic compounds and related substances has recently been shown to be receptor-madiated. In the present study, we have examined the effect of oral administration of the strong peroxisome proliferator fenofibrate on the hepatic expression level of the peroxisome proliferator activated receptor (PPAR) in rats. Immunoblots of rat liver cytosols and nuclear extracs using antibodies raised against recombinant PPAR/β-galactosidase fusion proteins revealed a pronounced increase in the amount of PPAR protein in response to fenofibrate treatment. This induction could also be confirmed at the level or RNA by Northern blotting. …

Male1303 BiochemistryReceptors Cytoplasmic and Nuclear10050 Institute of Pharmacology and ToxicologyPeroxisome proliferator-activated receptorPPARMicrobodiesPolymerase Chain ReactionBiochemistryPPAR agonist1307 Cell BiologyMiceCytosol1315 Structural BiologyFenofibrateStructural Biologychemistry.chemical_classificationMice Inbred BALB CFenofibrateOligodeoxyribonucleotidesPeroxisome proliferator-activated receptor alphaFusion proteinmedicine.drugmedicine.medical_specialtyPeroxisome proliferator-activated receptor gammamRNAMolecular Sequence DataBiophysicsPeroxisome ProliferationReceptors Cell Surface610 Medicine & healthBiology1311 GeneticsInternal medicine1312 Molecular BiologyGeneticsmedicineAnimalsNorthern blotMolecular BiologyAntibodyHypolipidemic compoundCell NucleusMessenger RNABase SequenceImmune SeraCell BiologyBlotting NorthernRatsMice Inbred C57BLEndocrinologychemistry570 Life sciences; biologyTranscription Factors1304 BiophysicsFEBS Letters
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STUDIO ETNOARCHEOMETRICO DI MALTE AEREE A LEGANTE GESSOSO NELL’AREA DELLE MADONIE (SICILIA SETTENTRIONALE)

2010

The Madonie Regional Park, which covers an area of about 400 square kilometres, is an ideal context where environment and man activities are still mixed harmoniously. In the last years a variety of ethno-archaeometric investigations have been carried out in order to study various aspects of the "material culture" of this territory. In particular, the research was focused on the production of majolica which have had a great importance since the early decades of the 16th century thanks to the geolithological features of the Madonie area, particularly rich in clayey raw material. The traditional building techniques of the Madonie which involve several typologies of building materials (used for…

gypsum-based mortars traditional kilns Northern SicilySettore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.
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Evidence of energy and nutrient transfer from invasive pink salmon ( Oncorhynchus gorbuscha ) spawners to juvenile Atlantic salmon ( Salmo salar ) an…

2020

EcologybiologyEcologyZoologyAquatic Sciencebiology.organism_classificationNorthern norwayBrown troutNutrientOncorhynchusJuvenileSalmoEcology Evolution Behavior and SystematicsIsotope analysisEcology of Freshwater Fish
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Statistical upscaling of ecosystem CO2 fluxes across the terrestrial tundra and boreal domain: Regional patterns and uncertainties

2021

The regional variability in tundra and boreal carbon dioxide (CO2) fluxes can be high, complicating efforts to quantify sink-source patterns across the entire region. Statistical models are increasingly used to predict (i.e., upscale) CO2 fluxes across large spatial domains, but the reliability of different modeling techniques, each with different specifications and assumptions, has not been assessed in detail. Here, we compile eddy covariance and chamber measurements of annual and growing season CO2 fluxes of gross primary productivity (GPP), ecosystem respiration (ER), and net ecosystem exchange (NEE) during 1990–2015 from 148 terrestrial high-latitude (i.e., tundra and boreal) sites to a…

hiilidioksidi0106 biological sciences010504 meteorology & atmospheric sciencesBiomeikiroutaNORTHERN PEATLANDAtmospheric sciences01 natural sciencesCarbon Dioxide/analysisSoilremote sensingArctic/dk/atira/pure/sustainabledevelopmentgoals/climate_actionSDG 13 - Climate ActionEXCHANGEComputingMilieux_MISCELLANEOUSGeneral Environmental ScienceARCTIC TUNDRA[SDU.OCEAN]Sciences of the Universe [physics]/Ocean Atmospherearktinen alueGlobal and Planetary ChangeCLIMATE-CHANGEEcologyCARBON-DIOXIDE BALANCEUncertaintyCO balancekasvihuonekaasutBLACK SPRUCE FORESTgreenhouse gasTerrestrial ecosystemSeasonsEcosystem respiration1171 GeosciencesEddy covariancepaikkatietoanalyysiSOIL-MOISTURE010603 evolutionary biology114 Physical sciencesEnvironmental Chemistry[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces environmentTundraEcosystem0105 earth and related environmental sciencesCO2 balanceReproducibility of ResultsENERGY FLUXES15. Life on landTundraPERMAFROST CARBONCarbonlandBorealhiilinielut13. Climate actionGROWING-SEASONSpatial ecologyEnvironmental scienceSpatial variabilitykaukokartoitusempiricalpermafrost
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Proteinase-3 mRNA expressed by glomerular epithelial cells correlates with crescent formation in Wegener's granulomatosis

2000

Proteinase-3 mRNA expressed by glomerular epithelial cells correlates with crescent formation in Wegener's granulomatosis. Background Wegener's granulomatosis (WG) is characterized by systemic vasculitis with crescentic glomerulonephritis (CGN) and circulating autoantibodies directed against neutrophil cytoplasmic antigens (ANCA). Proteinase 3 (PR-3), a neutral serine proteinase in neutrophils implicated in the growth control of myeloid cells, has been identified as the target antigen for ANCA in WG. Since the kidneys are frequently involved in WG, we studied the in situ expression of PR-3 by renal parenchymal cells. Methods We assessed the expression of PR-3 in kidney biopsies of 15 patien…

AdultMalePathologymedicine.medical_specialtyBiopsyMyeloblastinKidney GlomerulusIn situ hybridizationBiologyurologic and male genital diseasesKidneyvasculitisAntigenProteinase 3medicineRapidly progressive glomerulonephritisHumanscrescent glomerulonephritisNorthern blotRNA Messengerrapidly progressive glomerulonephritisCells CulturedAgedKidneyANCAurogenital systemSerine EndopeptidasesGranulomatosis with PolyangiitisEpithelial CellsMiddle Agedmedicine.diseasekidney parenchymal cellsmedicine.anatomical_structureKidney TubulesNephrologyImmunohistochemistryFemaleSystemic vasculitisKidney International
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Ladinia dolomitica

2020

Scopo di questo contributo è offrire una panoramica sull’area che viene usualmente definita “Ladinia dolomitica” e sulla varietà linguistica che vi viene tradizionalmente parlata, il ladino. L'articolo descrive brevemente la storia dell'area e dello sviluppo del ladino, e in seguito descrive le caratteristiche fonologiche, morfologiche, sintattiche e lessicali principali del ladino, che lo distinguono dalle vicine varietà italoromanze. In seguito si illustrano le peculiarità linguistiche dei singoli dialetti ladini, che sono parlati ognuno in una valle diversa delle Dolomiti. L'articolo è fortemente innovativo e originale, perché permette di ascoltare i file audio che esemplificano i tratti…

dialettologiagardeneseSettore L-FIL-LET/09 - Filologia E Linguistica RomanzalivinalleseFassanodiacronialingue di minoranzafodomSettore L-LIN/01 - Glottologia E LinguisticadialectologyretoromanzomorfologiaBadiottogrammatical descriptionRhaeto-romanceNorthern ItalysyntaxLivinallese Fodomphonology morphologyminority languageLadinsintassidiachronylessicosynchronyDolomitiDolomiteladinoAmpezzanosincroniaItalia del Norddescrizione grammaticalelexiconfonologia
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Synthesis and expression of MHC class II molecules in the absence of attached invariant chains by recombinant-interferon-gamma-activated bone-marrow-…

1987

Pure populations of in vitro propagated bone marrow-derived macrophages are constitutively Ia negative. Co-culturing of these cells with recombinant interferon-gamma (rIFN-gamma) resulted in the appearance of high amounts of Ia antigens at the cell surface of essentially all cells. The continuous presence of the stimulus was a prerequisite for sustained Ia expression because removal of the stimulus resulted in rapid decline of surface Ia. Two-dimensional (2D) gel analysis (1D isoelectric focusing, 2D sodium dodecyl sulfate-polyacrylamide gel electrophoresis) of class II molecules synthesized by rIFN-gamma-stimulated bone marrow macrophages (BMM phi) revealed that, in contrast to class II co…

ImmunologyBone Marrow Cellslaw.inventionInterferon-gammaMicelawImmunology and AllergyAnimalsNorthern blotRNA MessengerGel electrophoresisMessenger RNAMHC class IIMice Inbred C3HPolymorphism GeneticbiologyIsoelectric focusingMacrophagesHistocompatibility Antigens Class IIDNAMacrophage ActivationMolecular biologyIn vitroRecombinant ProteinsGene Expression RegulationRecombinant DNAbiology.proteinIntracellularEuropean journal of immunology
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A survey around the Italian pediatric units on current clinical practice for Sleep Disordered Breathing (SDB)

2019

Background During recent years, interest on Sleep Disordered Breathing (SDB) in pediatric age has increased, due to the impact on quality of life, psycho-physical attitude and other serious morbidities if undiagnosed and untreated. Methods Italian Pediatric Respiratory Diseases Society (SIMRI) SDB-Working Group carried out an exploratory survey in Italy, from January to December 2016, to assess the diagnostic and therapeutic pathways, perception and relevance of SDB in Italian Hospitals. Results A questionnaire was sent to 180 Pediatric Units (PUs) distributed throughout the Italy; 102 Pediatric Units (PUs; 56.6%) answered and among them 57% dealt with SDB, and 94% recognized SDB as a major…

Malemedicine.medical_specialtyPractice PatternsPolysomnographyChildren; Italy; Pediatric units; Sleep disordered breathing; Survey; Child; Female; Humans; Italy; Male; Practice Patterns Physicians'; Sleep Apnea Syndromes; Surveys and QuestionnairesChildren; Italy; Pediatric units; Sleep disordered breathing; Survey03 medical and health sciencesExploratory surveySleep Apnea Syndromes0302 clinical medicineQuality of lifeSurveys and Questionnaires030225 pediatricsmental disordersmedicineHumanscardiovascular diseases030212 general & internal medicinePractice Patterns Physicians'ChildPediatric unitsSurveyChildrenPhysicians'medicine.diagnostic_testSleep disordered breathingPediatric respiratory diseasesbusiness.industryResearchlcsh:RJ1-570lcsh:PediatricsPediatric agenervous system diseasesrespiratory tract diseasesNorthern italyClinical PracticeItalyEmergency medicineSleep disordered breathingFemalebusinessItalian Journal of Pediatrics
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Signals and memory in tree-ring width and density data

2015

It has been suggested that maximum latewood density (MXD) should be used instead of tree-ring width (TRW) data to reconstruct post-volcanic cooling effects. A thorough assessment of high frequency signals and potentially differing memory effects in long MXD and TRW chronologies, in response to large volcanic eruptions, is still missing, however. We here present a compilation of MXD and TRW chronologies from 11 sites in the Northern Hemisphere, covering the past 750+ years, and containing significant June–August temperature signals. Basic assessment of the data using Superposed Epoch Analysis reveals a temporally extended response in TRW, by 2–3 years, to large volcanic eruptions, though pos…

geographygeography.geographical_feature_categoryVulcanian eruptionEcologyAtmosphereDendroclimatologyNorthern HemisphereClimate changeGeologyPlant ScienceDendroclimatologyClimatic changesLatitudeEnvironmental sciencesVolcanoClimatologyPaleoclimatologyDendrochronologyWeather--Effect of volcanic eruptions onPaleoclimatologyGeologyDendrochronologia
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