0000000000380833

AUTHOR

Danai Vogiatzis

showing 3 related works from this author

Obesity and iron deficiency anemia as risk factors for asymptomatic bacteriuria.

2013

Background: Few studies examined the risk factors of asymptomatic bacteriuria, showing contradictory results. Our study aimed to examine the association between different clinical and laboratory parameters and asymptomatic bacteriuria in internal medicine patients. Materials and methods: 330 consecutive hospitalized subjects, asymptomatic for urinary tract infections (UTIs), underwent to microscopic examination of urine specimens. 100 subjects were positive for microscopic bacteriuria and were recruited into the study. At the quantitative urine culture 31 subjects of study population were positive while 69 subjects were negative for bacteriuria. Results: The analysis of clinical characteris…

Malemedicine.medical_specialtyBacteriuriaAnemiaUrinary systemUrineBacteriuriaurologic and male genital diseasesAsymptomaticRisk FactorsInternal medicineInternal MedicinemedicineHumansObesityAsymptomatic InfectionsAgedAnemia Iron-Deficiencybusiness.industryobesity anemia asymptomatic bacteriuriaOdds ratiobacterial infections and mycosesmedicine.diseasefemale genital diseases and pregnancy complicationsSurgeryIron-deficiency anemiaPopulation studyFemalemedicine.symptombusinessEuropean journal of internal medicine
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Genetics and Gene Therapy of Anderson-Fabry Disease.

2018

Fabry's disease is a genetic disorder of X-linked inheritance caused by mutations in the alpha galactosidase A gene resulting in deficiency of this lysosomal enzyme. The progressive accumulation of glycosphingolipids, caused by the inadequate enzymatic activity, is responsible of organ dysfunction and thus of clinical manifestations. In the presence of a high clinical suspicion, a careful physical examination and specific laboratory tests are required, finally diagnosis of Fabry's disease is confirmed by the demonstration of absence or reduced alpha-galactosidase A enzyme activity in hemizygous men and gene typing in heterozygous females; in fact the performance of enzymatic activity assay …

0301 basic medicineGenetic enhancementChaperone therapyDisease030204 cardiovascular system & hematologyBioinformaticsMice0302 clinical medicineAlpha galactosidase ADrug DiscoveryGenetics (clinical)KidneybiologyTrihexosylceramidesGenetic disorderEnzyme replacement therapyDependovirusRecombinant ProteinsAlpha galactosidase A; Chaperone therapy; Enzyme replacement therapy; Fabry disease; Gene therapy; Viral vectors; Molecular Medicine; Molecular Biology; Genetics; Drug Discovery3003 Pharmaceutical Science; Genetics (clinical)Isoenzymesmedicine.anatomical_structureMolecular Medicinemedicine.symptomGenetic Vectors03 medical and health sciencesGene therapyViral vectorRare DiseasesGeneticGeneticsmedicineAnimalsHumansEnzyme Replacement TherapyMolecular BiologyAlpha-galactosidasebusiness.industryDrug Discovery3003 Pharmaceutical ScienceOrgan dysfunctionGenetic Therapymedicine.diseaseFabry diseaseDisease Models Animal030104 developmental biologyalpha-GalactosidaseMutationbiology.proteinFabry DiseasebusinessBiomarkersCurrent gene therapy
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Large hiatal hernia at chest radiography in a woman with cardiorespiratory symptoms

2012

Hiatal hernia (HH) is a frequent entity. Rarely, it may exert a wide spectrum of clinical presentations mimicking acute cardiovascular events such as angina-like chest pain until manifestations of cardiac compression that can include postprandial syncope, exercise intolerance, respiratory function, recurrent acute heart failure, and hemodynamic collapse. A 69-year-old woman presented to the emergency department complaining of fatigue on exertion, cough, and episodes of restrosternal pain with less than 1 hour of duration. Her medical history only included some episodes of bronchitis and no history of hypertension. The 12-lead electrocardiogram demonstrated sinus rhythm with right bundle-bra…

Chest Painmedicine.medical_specialtyBundle-Branch BlockChest painHiatal herniaElectrocardiographymedicine.arteryInternal medicinemedicineHumansRespiratory functionSinus rhythmmedicine.diagnostic_testbusiness.industryGeneral Medicinemedicine.diseaseRadiographyHernia HiatalHeart failurePulmonary arteryEmergency MedicineCardiologyFemaleRadiologymedicine.symptomTransthoracic echocardiogramEmergency Service HospitalbusinessElectrocardiographyThe American Journal of Emergency Medicine
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