0000000000384514

AUTHOR

Silvia Facchini

showing 3 related works from this author

Impaired cognitive control in patients with brain tumors

2021

Though the assessment of cognitive functions is proven to be a reliable prognostic indicator in patients with brain tumors, some of these functions, such as cognitive control, are still rarely investigated. The objective of this study was to examine proactive and reactive control functions in patients with focal brain tumors and to identify lesioned brain areas more at "risk" for developing impairment of these functions. To this end, a group of twenty-two patients, candidate to surgery, were tested with an AX-CPT task and a Stroop task, along with a clinical neuropsychological assessment, and their performance was compared to that of a well-matched healthy control group. Although overall ac…

Brain MappingBrain NeoplasmsCognitive NeuroscienceReactive controlPrefrontal CortexExperimental and Cognitive PsychologyLesion-symptom mappingBrain tumorBehavioral NeuroscienceCognitionProactive controlAX-CPTReaction TimeHumansBrain tumor AX-CPT Stroop Lesion-symptom mapping Proactive control Reactive controlCognitive DysfunctionStroop
researchProduct

Systematic review and meta-analysis of the efficacy and safety of minocycline in schizophrenia

2017

ObjectiveOur aim was to perform an updated systematic review and meta-analysis on the efficacy and safety of adjunctive minocycline as a treatment of schizophrenia.MethodsWe conducted a PubMed/Scopus database search from inception to 3 February 2016 for randomized, placebo-controlled trials (RCTs), open non-randomized studies, and case reports/series evaluating minocycline in patients with schizophrenia. Random-effects meta-analysis of positive, negative, depressive, and cognitive symptom rating scales, discontinuation and adverse effects rates calculating standardized mean difference (SMD), and risk ratios±95% confidence intervals (CI95%) were calculated.ResultsSix RCTs were eligible (mino…

safetymedicine.medical_specialtyefficacyMinocyclinePlacebometa-analysi03 medical and health sciences0302 clinical medicinesystematic reviewInternal medicineefficacy; meta-analysis; Minocycline; safety; schizophrenia; systematic review; Neurology (clinical); Psychiatry and Mental HealthMedicineHumansRandomized Controlled Trials as TopicPositive and Negative Syndrome Scalebusiness.industryMinocycline schizophrenia efficacy safety meta-analysis systematic reviewConfidence interval030227 psychiatryDiscontinuationAnti-Bacterial Agentsmeta-analysisschizophreniaTolerabilityStrictly standardized mean differencePsychiatry and Mental HealthMeta-analysisAdjunctive treatmentNeurology (clinical)business030217 neurology & neurosurgeryAntipsychotic Agents
researchProduct

Weight loss is associated with improvements in cognitive function among overweight and obese people: A systematic review and meta-analysis

2017

Whilst obesity is associated with a higher risk of cognitive impairment, the influence of weight loss on cognitive function in obese/overweight people is equivocal. We conducted a meta-analysis of randomized controlled trials (RCTs) and longitudinal studies evaluating the influence of voluntary weight loss on cognitive function in obese/overweight individuals. Articles were acquired from a systematic search of major databases from inception till 01/2016. A random effect meta-analysis of weight loss interventions (diet, physical activity, bariatric surgery) on different cognitive domains (memory, attention, executive functions, language and motor speed) was conducted. Twenty studies (13 long…

Weight lossmedicine.medical_specialtyCognitive NeurosciencePhysical activity030209 endocrinology & metabolismOverweightlaw.invention03 medical and health sciencesBehavioral NeuroscienceCognition0302 clinical medicineRandomized controlled trialMemoryWeight losslawmedicineHumansAttentionObesityExerciseNutritionAttention; Cognition; Memory; Meta-analysis; Nutrition; Obesity; Physical activity; Weight loss; Exercise; Humans; Weight Loss; Cognition; Obesity; OverweightPhysical activityCognitionOverweightCognition Memory Attention Weight loss Obesity Meta-analysis Physical activity NutritionExecutive functionsmedicine.diseaseAttention; Cognition; Memory; Meta-analysis; Nutrition; Obesity; Physical activity; Weight loss; Neuropsychology and Physiological Psychology; Cognitive Neuroscience; Behavioral NeuroscienceObesityMeta-analysisNeuropsychology and Physiological PsychologyMeta-analysisPhysical therapymedicine.symptomPsychology030217 neurology & neurosurgeryNeuroscience & Biobehavioral Reviews
researchProduct