0000000000384524

AUTHOR

Domenico D'avella

showing 3 related works from this author

Impaired cognitive control in patients with brain tumors

2021

Though the assessment of cognitive functions is proven to be a reliable prognostic indicator in patients with brain tumors, some of these functions, such as cognitive control, are still rarely investigated. The objective of this study was to examine proactive and reactive control functions in patients with focal brain tumors and to identify lesioned brain areas more at "risk" for developing impairment of these functions. To this end, a group of twenty-two patients, candidate to surgery, were tested with an AX-CPT task and a Stroop task, along with a clinical neuropsychological assessment, and their performance was compared to that of a well-matched healthy control group. Although overall ac…

Brain MappingBrain NeoplasmsCognitive NeuroscienceReactive controlPrefrontal CortexExperimental and Cognitive PsychologyLesion-symptom mappingBrain tumorBehavioral NeuroscienceCognitionProactive controlAX-CPTReaction TimeHumansBrain tumor AX-CPT Stroop Lesion-symptom mapping Proactive control Reactive controlCognitive DysfunctionStroop
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Intravenous recombinant erythropoietin does not lead to an increase in cerebrospinal fluid erythropoietin concentration

2000

No abstract

Adultmedicine.medical_specialtyUltrasonography Doppler Transcranialmedicine.medical_treatmentSkull NeoplasmsElectrolytesIntraoperative PeriodCerebrospinal fluidPharmacokineticsInternal medicinemedicineHumansPulseRecombinant erythropoietinErythropoietinTransplantationChemotherapybusiness.industrySettore MED/27 - NeurochirurgiaErythropoietin transcranial dopplerRecombinant ProteinsEndocrinologyCytokineBlood-Brain BarrierNephrologyErythropoietinCerebrovascular CirculationInjections IntravenousIntravenous recombinant erythropoietin; cerebrospinal fluid; erythropoietin concentration.Femalebusinessmedicine.drug
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Expression of the tumor necrosis factor receptor—associated factors 1 and 2 and regulation of the nuclear factor—kB antiapoptotic activity in human g…

2005

Object. Tumor necrosis factor receptor (TNFR)—associated factors (TRAFs) are a recently established group of proteins involved in the intracellular signaling of the TNFR superfamily members. The TRAFs have been implicated in promoting cell survival through the activation of transcription factor nuclear factor (NF)—κB. The authors investigated the expression of NF-κB, caspase 3, TRAF1, TRAF2, and TRAF-associated NF-κB activator/TRAF—interacting protein (TANK/I-TRAF), a regulator of TRAF activity, in human gliomas. Methods. Tumor samples were obtained in 27 adult patients harboring seven low-grade gliomas, nine anaplastic astrocytomas, and 11 glioblastomas multiforme. The NF-κB activation was…

AdultMalePathologymedicine.medical_specialtyBlotting WesternTRAF1Apoptosis Blotting Brain Neoplasms/metabolism Brain Neoplasms/pathology Caspase GliomaApoptosisCaspase 3BiologyGliomamedicineHumansTranscription factorAgedAged 80 and overTankyrasesBrain NeoplasmsCaspase 3NF-kappa BGliomaMiddle AgedTNF Receptor-Associated Factor 2medicine.diseaseTNF Receptor-Associated Factor 1Up-RegulationIntracellular signal transductionBlotTumor Necrosis Factor Receptor-Associated FactorsCaspasesCancer researchFemaleTumor necrosis factor alphaSignal TransductionJournal of Neurosurgery
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