0000000000385850

AUTHOR

Katharina Heinze

showing 3 related works from this author

Differential impact of continuous theta-burst stimulation over left and right DLPFC on planning

2011

Most neuroimaging studies on planning report bilateral activations of the dorsolateral prefron- tal cortex (dlPFC). Recently, these concurrent activations of left and right dlPFC have been shown to dou- ble dissociate with different cognitive demands imposed by the planning task: Higher demands on the extraction of task-relevant information led to stronger activation in left dlPFC, whereas higher demands on the integration of interdependent information into a coherent action sequence entailed stronger activa- tion of right dlPFC. Here, we used continuous theta-burst stimulation (cTBS) to investigate the supposed causal structure-function mapping underlying this double dissociation. Two grou…

AdultMaleCTBSPrefrontal CortexPosterior parietal cortexStimulationbehavioral disciplines and activitiesFunctional LateralityLateralization of brain functionYoung AdultCognitionNeuroimagingParietal LobeCortex (anatomy)Reaction TimemedicineHumansRadiology Nuclear Medicine and imagingTheta RhythmPrefrontal cortexResearch ArticlesBrain MappingRadiological and Ultrasound TechnologyCognitionMagnetic Resonance ImagingTranscranial Magnetic Stimulationmedicine.anatomical_structureNeurologyFemaleNeurology (clinical)AnatomyPsychologyNeurosciencePsychomotor Performancepsychological phenomena and processesHuman Brain Mapping
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Transcranial direct current stimulation over left and right DLPFC: Lateralized effects on planning performance and related eye movements.

2014

Left and right dorsolateral prefrontal cortex (dlPFC) were recently found to be differentially affected by unilateral continuous theta-burst stimulation, reflected in an oppositional alteration of initial thinking time (ITT) in the Tower of London planning task. Here, we further explored this finding using bilateral transcranial direct current stimulation (tDCS) and simultaneous tracking of eye movements. Results revealed a decrease in ITT during concurrent cathodal tDCS of left dlPFC and anodal tDCS of right dlPFC. Eye-movement analyses showed that this facilitating tDCS effect was associated with the actual planning phase, thus reflecting a planning-specific impact of stimulation. For the…

Left and rightAdultMaleAnodal tdcsmedicine.medical_specialtyEye Movementsmedicine.medical_treatmentPrefrontal CortexStimulationAudiologyTranscranial Direct Current Stimulationbehavioral disciplines and activitiesFunctional LateralityYoung AdultHemispheric asymmetrymental disordersTask Performance and AnalysismedicineHumansTranscranial direct-current stimulationGeneral NeuroscienceEye movementGazeDorsolateral prefrontal cortexNeuropsychology and Physiological Psychologymedicine.anatomical_structurenervous systemFemalePsychologypsychological phenomena and processesCognitive psychologyBiological psychology
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Linking planning performance and gray matter density in mid-dorsolateral prefrontal cortex: Moderating effects of age and sex

2012

Abstract Planning of behavior relies on the integrity of the mid-dorsolateral prefrontal cortex (mid-dlPFC). Yet, only indirect evidence exists on the association of protracted maturation of dlPFC and continuing gains in planning performance post adolescence. Here, gray matter density of mid-dlPFC in young, healthy adults (18–32 years) was regressed onto performance on the Tower of London planning task while accounting for moderating effects of age and sex on this interrelation. Multiple regression analysis revealed an association of planning performance and mid-dlPFC gray matter density that was especially strong in late adolescence and early twenties. As expected, for males better plannin…

AdultMaleAdolescentCognitive NeuroscienceSynaptic pruningPrefrontal Cortexbehavioral disciplines and activities050105 experimental psychologyDevelopmental psychologyThinkingYoung Adult03 medical and health sciencesSex Factors0302 clinical medicineImage Interpretation Computer-Assistedmental disordersmedicineHumans0501 psychology and cognitive sciencesPrefrontal cortexProblem SolvingBrain Mapping05 social sciencesAge FactorsRegression analysisVoxel-based morphometryModerationMagnetic Resonance ImagingRegressionSexual dimorphismDorsolateral prefrontal cortexmedicine.anatomical_structurenervous systemNeurologyFemalePsychologypsychological phenomena and processes030217 neurology & neurosurgeryNeuroImage
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