0000000000387169

AUTHOR

Ursula Turpeinen

showing 3 related works from this author

DIFFERENTIAL INFLUENCE OF PERIPHERAL AND SYSTEMIC SEX STEROIDS ON SKELETAL MUSCLE QUALITY IN PRE- AND POSTMENOPAUSAL WOMEN.

2011

Aging is associated with gradual decline of skeletal muscle strength and mass often leading to diminished muscle quality. This phenomenon is known as sarcopenia and affects about 30% of the over 60-year-old population. Androgens act as anabolic agents regulating muscle mass and improving muscle performance. The role of female sex steroids as well as the ability of skeletal muscle tissue to locally produce sex steroids has been less extensively studied. We show that despite the extensive systemic deficit of sex steroid hormones in postmenopausal compared to premenopausal women, the hormone content of skeletal muscle does not follow the same trend. In contrast to the systemic levels, muscle t…

naisetpaikallinen ja systeeminen steroidogeneesiluustolihasvaihdevuodetskeletal musclelocal and systemic steroidogenesisikä
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Differential influence of peripheral and systemic sex steroids on skeletal muscle quality in pre- and postmenopausal women

2011

Aging is associated with gradual decline of skeletal muscle strength and mass often leading to diminished muscle quality. This phenomenon is known as sarcopenia and affects about 30% of the over 60-year-old population. Androgens act as anabolic agents regulating muscle mass and improving muscle performance. The role of female sex steroids as well as the ability of skeletal muscle tissue to locally produce sex steroids has been less extensively studied. We show that despite the extensive systemic deficit of sex steroid hormones in postmenopausal compared to premenopausal women, the hormone content of skeletal muscle does not follow the same trend. In contrast to the systemic levels, muscle t…

Muscle tissue0303 health sciencesAgingmedicine.medical_specialtyeducation.field_of_studyPopulationDehydroepiandrosteroneSkeletal muscle030209 endocrinology & metabolismCell BiologyBiologymedicine.disease03 medical and health sciences0302 clinical medicineEndocrinologymedicine.anatomical_structureSarcopeniaInternal medicinemedicineAndrostenedioneeducationTestosterone030304 developmental biologyHormoneAging Cell
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Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs

2009

We investigated whether long-term hormone replacement therapy (HRT) is associated with mobility and lower limb muscle performance and composition in postmenopausal women. Fifteen 54- to 62-yr-old monozygotic female twin pairs discordant for HRT were recruited from the Finnish Twin Cohort. Habitual (HWS) and maximal (MWS) walking speeds over 10 m, thigh muscle composition, lower body muscle power assessed as vertical jumping height, and maximal isometric hand grip and knee extension strengths were measured. Intrapair differences (IPD%) with 95% confidence intervals (CI) were calculated. The mean duration of HRT use was 6.9 ± 4.1 yr. MWS was on average 7% (0.9 to 13.1%, P = 0.019) and muscle…

SenescenceAgingmedicine.medical_specialtyvaihdevuodetPhysiologyMonozygotic twinWalkingIsometric ContractionPhysiology (medical)Internal medicineIkääntymienmedicineHumansMuscle Skeletalmuscle powersukupuolihormonitHand Strengthbusiness.industryEstrogen Replacement TherapySkeletal muscleEstrogenslihaksen voimantuottotehoTwins MonozygoticMiddle Agedmedicine.diseaseTwin studyTwin Studies as TopicMenopauseEndocrinologymedicine.anatomical_structureTransgender hormone therapyAgeingTwin Studies as TopicFemaleMenopauseTomography X-Ray ComputedbusinessMuscle ContractionlihasvoimaJournal of Applied Physiology
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