0000000000387332

AUTHOR

Blandine Comte

showing 7 related works from this author

DHA dose-dependently reduces atherosclerosis: a putative role for its peroxidation metabolites, F4-Neuroprostanes

2013

International audience

[SDV] Life Sciences [q-bio][SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[SDV.IDA] Life Sciences [q-bio]/Food engineeringComputingMilieux_MISCELLANEOUS
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The paradox of omega 3 PUFAs: autoprotection although highly susceptible to peroxidation

2013

National audience

[SDV] Life Sciences [q-bio][SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[SDV.IDA] Life Sciences [q-bio]/Food engineeringComputingMilieux_MISCELLANEOUS
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Anti-atherogenic action of DHA in LDLR-/- mice: are DHA oxygenated metabolites players in the resolution of inflammation?

2012

National audience

[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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An Early Stage Researcher's Primer on Systems Medicine Terminology

2021

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. Thes…

computer_scienceGraphs and NetworksmedicineGlossary[SDV]Life Sciences [q-bio]Comprehensive ReviewTerminology03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingMachine learningGeneticsmultiscale data science[INFO]Computer Science [cs]systems medicinemulti-scale modellingMulti-scale modellingComputingMilieux_MISCELLANEOUS030304 developmental biologyInterdisciplinarityMulti-scale data science0303 health scienceshealthGeneral MedicineHuman bodySciences bio-médicales et agricolesData science[SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]multiscale modeling3. Good healthTerm (time)Systems medicinemachine learningmulti-scale data scienceSystems medicineMedicine/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being030217 neurology & neurosurgeryNetwork and Systems Medicine
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Pre-slaughter stress and lipoperoxidation : protective effect of vitamin E and plant extracts rich in polyphenols given to finishing cattle

2009

National audience

[SDV] Life Sciences [q-bio][SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[INFO]Computer Science [cs][SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[SHS] Humanities and Social Sciences[INFO] Computer Science [cs][SDV.IDA] Life Sciences [q-bio]/Food engineeringComputingMilieux_MISCELLANEOUS[SHS]Humanities and Social Sciences
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Atheroprotective effects and peroxidation of docosahexaenoic acid: is there a direct link?

2012

International audience

[SDV] Life Sciences [q-bio][SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering[SDV]Life Sciences [q-bio][SDV.IDA]Life Sciences [q-bio]/Food engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering[SDV.IDA] Life Sciences [q-bio]/Food engineeringComputingMilieux_MISCELLANEOUS
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Lipid profiling following intake of the Omega 3 fatty acid DHA identifies the peroxidized metabolites F-4-Neuroprostanes as the best predictors of at…

2014

International audience; The anti-atherogenic effects of omega 3 fatty acids, namely eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) are well recognized but the impact of dietary intake on bioactive lipid mediat or profiles remains unclear. Such a profiling effort may offer novel targets for future studies into the mechanism of action of omega 3 fatty acids. The present study aimed to determine the impact of DHA supplementation on the profiles of polyunsaturated fatty acids (PUFA) oxygenated metabolites and to investigate their contribution to therosclerosis prevention. A special emphasis was given to the non-enzymatic metabolites knowing the high susceptibility of DHA to free radical…

MouseBlood PressureCardiovascularBiochemistryMice0302 clinical medicineTandem Mass SpectrometryAetiologylcsh:Sciencechemistry.chemical_classificationLiquid0303 health sciences[CHIM.ORGA]Chemical Sciences/Organic chemistryFatty Acidsanti-atherogenic;omega 3 fatty acids;epa;dha;bioactive lipid;atherosclerosis;pufas;effects;molecularLipids3. Good healthFatty Acids UnsaturatedMedicinemedicine.medical_specialtyanti-atherogenicKnockoutAortic DiseasesMédecine humaine et pathologieGas Chromatography-Mass SpectrometryLDLDose-Response RelationshipLipid Mediators03 medical and health sciencesomega 3 fatty acids[ CHIM.ORGA ] Chemical Sciences/Organic chemistryacide gras n 3Complementary and Integrative HealtheffectsBiologybioactive lipidDose-Response Relationship DrugPreventionlcsh:RathéroscléroseEPALipid MetabolismPrevention of disease and conditionsmedicine.diseaseEndocrinologychemistryNeuroprostaneslcsh:QHuman health and pathologyBiomarkersand promotion of well-beinglcsh:Medicine030204 cardiovascular system & hematologymedicine.disease_causeOral and gastrointestinalHeart RateReceptorsBlood plasmaCluster Analysis2.1 Biological and endogenous factorsMice KnockoutUnsaturatedChromatographyMultidisciplinaryFatty liverAnimal ModelsDHALiverBiochemistryDocosahexaenoic acidlipids (amino acids peptides and proteins)DrugResearch ArticlePolyunsaturated fatty acidDocosahexaenoic AcidsClinical Research DesignGeneral Science & TechnologyBiologyModel OrganismsInternal medicinemedicineAnimalsNeuroprostanesAnimal Models of Diseasemolecular3.3 Nutrition and chemopreventionOmega 3 fatty acidNutrition030304 developmental biologyAnalysis of Varianceacide docosahexaénoiqueLipid metabolismAtherosclerosis[SDV.AEN] Life Sciences [q-bio]/Food and NutritionReceptors LDLPUFAs[SDV.AEN]Life Sciences [q-bio]/Food and NutritionOxidative stressChromatography Liquid
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