0000000000388452

AUTHOR

Jacob M. Wilson

showing 2 related works from this author

Influence of HMB Supplementation and Resistance Training on Cytokine Response to Resistance Exercise

2014

The purpose of this study was to determine the effects of a multinutritional supplement including amino acids, β-hydroxy-β-methylbutyrate (HMB), and carbohydrates on cytokine responses to resistance exercise and training.Seventeen healthy, college-aged men were randomly assigned to a Muscle Armor™ (MA; Abbott Nutrition, Columbus, OH) or placebo supplement group and 12 weeks of resistance training. An acute resistance exercise protocol was administered at 0, 6, and 12 weeks of training. Venous blood samples at pre-, immediately post-, and 30-minutes postexercise were analyzed via bead multiplex immunoassay for 17 cytokines.After 12 weeks of training, the MA group exhibited decreased interfer…

Malemedicine.medical_specialtyStrength trainingmedicine.medical_treatmentInterleukin-1betaMedicine (miscellaneous)Immune functionGranulocytePlaceboBody Mass IndexInterferon-gammaYoung AdultDouble-Blind MethodMuscle damageInternal medicineMyokineMyokinemedicineDietary CarbohydratesValeratesHumansMicronutrientsAmino Acidsta315Chemokine CCL4Immune function; Muscle damage; Myokine; Nutrition; Strength trainingChemokine CCL2NutritionNutrition and DieteticsInterleukin-13business.industryInterleukin-6MonocyteBody WeightInterleukin-8InterleukinResistance TrainingVenous bloodHealthy VolunteersInterleukin-10Cytokinemedicine.anatomical_structureEndocrinologyNutrition AssessmentImmunologyDietary SupplementsCytokinesStrength trainingbusiness
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α-Hydroxy-Isocaproic Acid (HICA)—Effects on Body Composition, Muscle Soreness and Athletic Performance

2013

Alfa-hydroxy-isocaproic acid (HICA) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. Clinical and experimental studies indicate that HICA may be considered as an anti-catabolic substance. Intensive exercise leads not only to anabolism but also to catabolism in the muscle. The latter is associated with breakdown of muscle proteins and delayed-onset muscle soreness (DOMS). Several studies indicate that free branched-chain amino acids (BCAAs), especially leucine, and their transaminated metabolites, such as α-ketoisocaproic acid (KIC), may alleviate symptoms associated with exercise-induced catabolism. Recent findings suggest that HICA effectively …

chemistry.chemical_classificationmedicine.medical_specialtyAnabolismCatabolismIsocaproic acidConnective tissueBiologyAmino acidProtein catabolismEndocrinologymedicine.anatomical_structureBiochemistrychemistryInternal medicinemedicineComposition (visual arts)Leucine
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