0000000000388537

AUTHOR

Luigi Gradoni

showing 4 related works from this author

Monitoring campaign over an edible dormouse population (Glis glis; rodentia: Gliridae) in Sicily: First report of mesocestodiasis

2021

Simple Summary In Nebrodi Park (Sicily, Italy), live many wild mammal species that move closer to human beings every day. The edible dormouse (Glis glis), in 2017 and 2018, was responsible for nut crop damage in the area. For this reason, a sanitary monitoring campaign involving 30 dormice was carried out by collecting rectal and conjunctival swabs and fur and nest content, which were then processed for laboratory examinations. A large presence of fleas belonging to Monopsyllus sciurorum was found. Necropsy of a dead dormouse revealed an infection of Mesocestoides lineatus, whose cysts were found in the abdomen cavity and on the liver; this is the first report of this in this species. Furth…

0301 basic medicineMesocestoides lineatus030231 tropical medicinePopulationSettore BIO/05 - ZoologiaZoologyCrop (anatomy)ArticleMesocestoides lineatus03 medical and health sciences0302 clinical medicineNestbiology.animallcsh:Zoologylcsh:QL1-991DormouseeducationEdible dormouseeducation.field_of_studyDormicelcsh:Veterinary medicineGeneral Veterinarybiology<i>Glis glis<i>biology.organism_classification<i>Monopsyllus sciorum<i>030104 developmental biologylcsh:SF600-1100Monopsyllus sciorumAnimal Science and Zoology<i>Mesocestoides lineatus<i></i></i></i></i></i></i>Glis glis
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A 6 day course of liposomal amphotericin B in the treatment of infantile visceral leishmaniasis: the Italian experience

2004

Objectives To evaluate in a retrospective analysis the efficacy and safety of a 6 day course of liposomal amphotericin B (L-AmB) in infantile cases of Mediterranean visceral leishmaniasis (VL) diagnosed over a 10 year period in Italy. Patients and methods Patients included were diagnosed as having VL consecutively admitted from December 1992 to December 2001 at four main referral children's hospitals in Italy and treated with six intravenous doses of 3 mg/kg L-AmB given on days 1-5 and 10 (a total dose of 18 mg/kg). Demographic data, nutritional status, underlying diseases, clinical and laboratory findings, and therapy outcome were considered. Results A total of 164 HIV-negative children (m…

MaleMicrobiology (medical)medicine.medical_specialtyAdolescentFeverAntiprotozoal AgentsFluorescent Antibody TechniqueNutritional Statusitaly; leishmania infantum; therapyBone MarrowRecurrenceAmphotericin BInternal medicineAmphotericin BmedicineHumansPharmacology (medical)ChildAdverse effectleishmaniasisRetrospective StudiesPharmacologyDrug Carriersbiologybusiness.industryInfantRetrospective cohort studyLeishmaniasismedicine.diseasebiology.organism_classificationSurgeryRegimenTreatment OutcomeInfectious DiseasesVisceral leishmaniasisItalyEl NiñoChild PreschoolLiposomesLeishmaniasis VisceralFemaleLeishmania infantumbusinessmedicine.drug
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EPIDEMIOLOGICAL SURVEILLANCE OF VISCERAL LEISHMANIASIS IN SICILY, ITALY

1997

Abstract Visceral leishmaniasis (VL) is endemic in Sicily. Although it is a notifiable disease, there is evidence that the actual number of cases is higher than that reported. In 1987, a regional reference center for active surveillance of VL was established and it recorded a total of 284 cases through 1995, a mean of 31.5 cases/year and about four-fold more than previously reported. Of the 284 cases, 150 (53%) were children (≤ 14 years of age), and of the 134 adults, 39 (29%) were coinfected with human immunodeficiency virus (HIV). The commonest viscerotropic zymodeme of Leishmania infantum, MON 1, was identified in 40 (93%) of 43 HIV-negative and eight (57%) of 14 HIV-positive patients. A…

AdultMalemedicine.medical_specialtyAdolescentAllopurinolMeglumine antimoniateNotifiable diseaseAntiprotozoal AgentsHIV InfectionsCohort StudiesAge DistributionMeglumineRecurrenceAmphotericin BVirologyInternal medicineAmphotericin BEpidemiologyOrganometallic CompoundsmedicineAnimalsHumansLeishmania infantumSex DistributionChildSicilyleishmaniasisAgedMeglumine Antimoniatebiologybusiness.industryInfantLeishmaniasisMiddle Agedbiology.organism_classificationmedicine.diseaseSurgeryInfectious DiseasesVisceral leishmaniasisChild PreschoolLeishmaniasis VisceralAntimonialDrug Therapy CombinationFemaleParasitologyLeishmania infantumbusinessmedicine.drug
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EARLY EFFICACY OF LIPOSOMAL AMPHOTERICIN B IN THE TREATMENT OF VISCERAL LEISHMANIASIS

1996

The rapidity and efficacy of a short course of liposomal amphotericin B was evaluated in 29 children affected by visceral leishmaniasis (Leishmania infantum). Their overall health status was assessed using the prognostic inflammatory and nutritional index (PINI), and their haematological status by the reticulocyte count and haemoglobin blood levels. All these quantities were measured on day 0, and 3 and 10 d after starting therapy. A significant decrease of inflammatory signs, associated with an improved reticulocyte count, was recorded after 3 d of therapy. A significant increase of haemoglobin levels was also observed 10 d after the start of treatment. The early reduction of inflammatory …

Malemedicine.medical_specialtyAdolescentmedicine.medical_treatmentAntiprotozoal AgentsSeverity of Illness IndexGastroenterologyAmphotericin BAmphotericin BInternal medicineAnimalsHumansMedicineLeishmania infantumChildleishmaniasisDrug CarriersChemotherapybiologybusiness.industryPublic Health Environmental and Occupational HealthInfantAnemiaLeishmaniasisGeneral Medicinebiology.organism_classificationmedicine.diseaseInfectious Diseasesmedicine.anatomical_structureVisceral leishmaniasisItalyChild PreschoolLiposomesImmunologyLeishmaniasis VisceralFemaleParasitologyLiposomal amphotericinHemoglobinBone marrowLeishmania infantumbusinessmedicine.drug
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