0000000000389177

AUTHOR

Stéphan Haulon

showing 2 related works from this author

Impact of Thoracic Endografting on the Hemodynamics of the Native Aorta: Pre- and Postoperative Assessments of Wall Shear Stress and Vorticity Using …

2021

Purpose To quantify the hemodynamic consequences of thoracic endovascular aortic repair (TEVAR) by comparing the preoperative and postoperative wall shear stress (WSS) and vorticity profiles on computational fluid dynamics (CFD) simulations. Materials and Methods The pre- and postoperative computed tomography (CT) scans from 20 consecutive patients (median age 69 years, range 20–87) treated for different thoracic aortic pathologies (11 aneurysms, 5 false aneurysms, 3 penetrating ulcers, and 1 traumatic aortic rupture) were segmented to construct patient-specific CFD models using a meshless code. The simulations were run over the cardiac cycle, and the WSS and vorticity values measured at th…

Adultmedicine.medical_specialty[SDV]Life Sciences [q-bio]HemodynamicsAorta Thoracic030204 cardiovascular system & hematologyComputational fluid dynamicsAortic repair030218 nuclear medicine & medical imaging03 medical and health sciencesYoung Adult0302 clinical medicinemedicine.arteryInternal medicineShear stressmedicineThoracic aortaHumansRadiology Nuclear Medicine and imagingComputingMilieux_MISCELLANEOUSAortaAgedAged 80 and overAortabusiness.industryHemodynamicsModels CardiovascularVorticityMiddle AgedTreatment Outcomecardiovascular systemCardiologyHydrodynamicsSurgeryStentsCardiology and Cardiovascular MedicinebusinessJournal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
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Polyester vascular prostheses coated with a cyclodextrin polymer and activated with antibiotics: Cytotoxicity and microbiological evaluation

2008

Abstract Polyester (PET) vascular grafts are used to replace or bypass damaged arteries. To minimize the risk of infection during and after surgical interventions, a PET vascular prosthesis (Polythese®) was functionalized with cyclodextrin polymers (PolyCDs) in order to obtain the controlled release of antibiotics (ABs: ciprofloxacin, vancomcyin and rifampicin). An epithelial cell line (L132) was used to determine the viability of the antibiotics, and human pulmonary microvascular endothelial cells (HPMEC) were used for cell proliferation by cell counting and cell vitality with Alamar Blue fluorescent dye. Staphylococcus aureus, Escherichia coli and Enteroccocus sp. were used to determine t…

Staphylococcus aureusMaterials scienceCell Survivalmedicine.drug_classPolyestersAntibioticsBiomedical EngineeringMicrobial Sensitivity TestsProsthesis DesignBiochemistryMicrobiologyBiomaterialsMinimum inhibitory concentrationCiprofloxacinVancomycinIn vivoEscherichia colimedicineHumansCelluloseCytotoxicityMolecular BiologyCyclodextrinsGeneral MedicineAntimicrobialAnti-Bacterial AgentsBlood Vessel ProsthesisCiprofloxacinSpectrophotometryToxicityVancomycinRifampinEnterococcusBiotechnologymedicine.drugActa Biomaterialia
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