0000000000390738
AUTHOR
M Brecx
Healing of intrabony defects following treatment with a bovine-derived xenograft and collagen membrane
Objectif: L'objectif de cette etude etait de comparer cliniquement le traitement de lesions intra-osseuses profondes avec xenogreffe d'origine bovine (BDX) associe a une membrane collagene bioresorbable pour acceder a la chirurgie a lambeau. Methode: Vingt-huit malades souffrant de parodontite chronique, chacun montrant une lesion intra-osseuse ont ete traites au hasard au BDX+membrane collagene (essai) ou avec chirurgie a lambeau (controle). Les mesures des tissus mous ont ete prises au depart et 1 an apres la therapie. Resultats: Aucune difference dans aucun des parametres etudies n'a ete observee au depart entre les deux groupes. La cicatrisation a ete sans incident pour tous les malades…
Non-surgical periodontal treatment with a new ultrasonic device (Vectortm-ultrasonic system) or hand instruments. A prospective, controlled clinical study
Objectives: The aim of this prospective, randomized, controlled clinical study was to compare the effectiveness of a newly developed ultrasonic device to that of scaling and root planing for non-surgical periodontal treatment. Material and Methods: Thirty-eight patients with moderate to advanced chronic periodontal disease were treated according to an “one-stage procedure” with either a newly developed ultrasonic device (VUS) (Vector™-ultrasonic system) or scaling and root planing (SRP) using hand instruments. Clinical assessments by plaque index (PlI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), gingival recession (GR), and clinical attachment level (CAL) were made …
Immunohistochemical evaluation of matrix molecules associated with wound healing following treatment with an enamel matrix protein derivative in humans
Application of enamel matrix protein derivative (EMD) onto a debrided and conditioned root surface has been shown to promote periodontal regeneration in animals and humans. However, until now there is virtually no information from humans describing the expression of different matrix molecules in the newly formed periodontal tissues following treatment with EMD. This study investigated immunohistochemically in humans the expression of matrix molecules associated with periodontal tissues reformed after treatment with EMD. Eight patients with intrabony defects were treated with EMD. Six months after surgery teeth together with some of their surrounding soft and hard tissues were removed, fixed…
Five-year results following treatment of intrabony defects with enamel matrix proteins and guided tissue regeneration
Treatment with enamel matrix proteins (EMD) or guided tissue regeneration (GTR) has been shown to enhance periodontal regeneration. However, until now there are limited data on the long-term results following these treatment modalities.The aim of the present clinical study was to present the 5-year results following treatment of intrabony defects with EMD, GTR, combination of EMD and GTR, and open flap debridement (OFD).Forty-two patients, each of whom displayed one intrabony defect of a probing depth of at least 6 mm, were randomly treated with one of the four treatment modalities. The following parameters were evaluated prior to surgery, at 1 year and at 5 years after: plaque index, gingi…
Immunohistochemical investigation on the pattern of vimentin expression in regenerated and intact monkey and human periodontal ligament.
The expression of vimentin is well documented in the intact animal and human periodontal ligament (PDL), but there is limited information on the pattern of vimentin expression in the regenerated PDL. The aim of the present study was to investigate the pattern of vimentin expression in the regenerated and intact monkey and human PDL. A total of 12 chronic recession-type defects were created in three monkeys (Macaca fascicularis) and treated either with guided tissue regeneration (GTR), or with an enamel matrix protein derivative (EMD). After 5 months, the animals were sacrificed and specimens containing the defects and surrounding tissues were dissected free, decalcified in EDTA and embedded…