Chronic rhinosinusitis with nasal polyps impact in severe asthma patients: Evidences from the Severe Asthma Network Italy (SANI) registry

Abstract Background The clinical and laboratory features of patients enrolled in the Severe Asthma Network in Italy (SANI) registry, a web-based observatory collecting demographic, clinical, functional and inflammatory data of patients with severe asthma were evaluated, with a special emphasis to chronic rhinosinusitis with nasal polyposis (CRSwNP). Methods For each eligible patients the following information has been collected: demographic data, clinical features, asthma control in the previous month according to the GINA (Global INitiative for Asthma) Guidelines and standardized questionnaires, concomitant regular and on demand treatments and inflammatory markers. Results 695 patients wit…

Effect of the inclusion of lemon citrus pulp in the diet of Valle del Belice lactating ewes. Milk production and composition.

Lemon citrus pulp residues from the citrus juice industry; it belongs to the citrus by-product that are more extensively used for livestock feeding. Furthermore, citrus pulp is a source of flavonoids such as hesperidin and naringin, which have antioxidant properties. This study aimed to investigate the effect of fresh lemon citrus pulp (LP) as natural antioxidant, on feeding behavior, milk yield and milk quality of Valle del Belice lactating ewes in the hot summer season in Sicily. A total of 15 second lambing ewes were individually allocated in 3¥3 m box and fed with 3 diets in a 3 ¥ 3 Latin square design, with 3 phases composed of 21 days. The diets were: LP0, mixed hay ad libitum plus 60…

Reply to: Kow CS et al. Are severe asthma patients at higher risk of developing severe outcomes from COVID-19?

Adherence to colchicine treatment and colchicine resistance in a multicentric FMF national cohort

Introduction: Colchicine is the standard treatment for Familiar Mediterranean Fever (FMF), however about 5% of patients (pts) experience colchicine resistance. There is no standard definition of colchicine resistance. Recently a panel of experts elaborated a new definition based on a Delphi consensus approach. Objectives: We aim to describe main features of the disease and clinical outcome of a cohort of FMF pts with particular interest on the colchicine resistance and tolerability according to the definitions proposed by the recent consensus.

The effects of the traditional producing system on physicochemical, microbial and sensory properties of Caciocavallo Palermitano cheese

Caciocavallo Palermitano (CP) is a traditional cheese made with raw milk from cows of Sicilian local breeds fed pasture-based diets in extensive farms (EXT), processed by an artisanal technology (ART) based on wooden tools and the action of native microflora. CP is obtained also in intensive farms (INT) where milk from cows of specialized breeds fed dry diets is transformed by advanced procedures (ADV) using a stainless steel equipment and lactic acid starter cultures. This research was planned to investigate the changes in cheese properties due to production system and ripening., Milk was collected 3 times from an EXT and an INT farm and processed in ART and ADV conditions. The 12 produced…