0000000000393679

AUTHOR

M. Cervera

showing 2 related works from this author

Influence of Several Effectors on the Structure-Activity Relationship of Spleen Phosphodiesterase

1993

The influence of Mg(II) and organic solvents on the structure-activity relationship of spleen phosphodiesterase II was analyzed using UV and fluorescence spectroscopies. An increase in the RNase activity found in the presence of Mg(II) was related to the enzyme-Mg(II) interaction detected by UV spectroscopy. In the fluorescence spectra of phosphodiesterase strong hypochromic and bathochromic effects were observed when RNA was present at a concentration (52 μg ml−1) of the same magnitude as the concentration that inhibits the activity (Ki = 40 μg ml−1). The strong quenching observed in the presence of RNA shows the importance of large dynamic and static quenching of the Trp residues of the e…

chemistry.chemical_classificationQuenching (fluorescence)ChemistryPhosphodiesteraseBiochemistryFluorescenceCatalysisFluorescence spectroscopyUltraviolet visible spectroscopyEnzymeBiochemistryBathochromic shiftBiophysicsDenaturation (biochemistry)General Agricultural and Biological SciencesBiotechnologyBiocatalysis
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Iris Claw Phakic Lens—Intermediate and Long-term Corneal Endothelial Changes

1994

OBJECTIVE: To study the alterations in the corneal endothelial layer two years after the implantation of iris claw phakic lenses. STUDY DESIGN: Prospective study of postoperative results with a minimum follow-up of 6 months, maximum of two years and a mean of 14 months. SETTING: Department of Ophthalmology, ‘La Fe’ University Hospital, Department of Surgery of Valencia School of Medicine, Valencia, Spain. PATIENTS: Ninety eyes of 70 patients presenting high myopia who underwent anterior chamber phakic lens implantation with iris fixation IOLs in the last two years. MAIN OUTCOME MEASURES: Non-contact specular microscopy with video image system was used to perform examination of the corneal e…

medicine.medical_specialtyCorneal endotheliumgenetic structuresEndotheliumbusiness.industryHigh myopiaUniversity hospitaleye diseasesSurgeryOphthalmologymedicine.anatomical_structureOphthalmologymedicinesense organsIris (anatomy)businessIris clawProspective cohort studyFixation (histology)European journal of Implant and Refractive Surgery
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